Aromatic rings are highly stable due to the arrangement of the π-electrons situated above and below the plane of the aromatic ring, which form a π-electron cloud. 319-03-9, Name is 5-Fluoroisobenzofuran-1,3-dione, molecular formula is C8H3FO3, belongs to benzoxazole compound. In a document, author is Tasci, Meryem, Quality Control of 5-Fluoroisobenzofuran-1,3-dione.
In the present study, a series of nine novel 5-substituted-2-(p-tert-butylphenyl)benzoxazole derivatives have been synthesized and their structures confirmed by spectral techniques and also tested for their antimicrobial activities. The minimum inhibitory concentrations (MIC) of the new benzoxazoles have been determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs. The new benzoxazole derivatives are found to possess a broad spectrum of antibacterial activity with MIC values of 8-256 mu g/mL. Especially, compound 9 is more active than standard drugs ciprofloxacin and cefotaxime against E. coli isolate with a MIC value of 8 mu g/mL. Also new compounds are less active than fluconazole with a MIC value of 256 mu g/mL against C. albicans and its isolate except for compound 9 that shows better activity other compounds with a MIC value of >4 mu g/mL for their antifungal activity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about C8H3FO3. Quality Control of 5-Fluoroisobenzofuran-1,3-dione.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem