Reference of 352-34-1, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 352-34-1, Name is 1-Fluoro-4-iodobenzene, SMILES is FC1=CC=C(I)C=C1, belongs to benzoxazole compound. In a article, author is Lu, Ju-You, introduce new discover of the category.
Ligand-free synthesis of 2-aminoarylbenzoxazoles via copper-catalyzed C-N/C-O coupling
A copper-catalyzed C-N/C-O coupling has been developed for synthesis of 2-aminoarylbenzoxazole derivatives. The protocol uses readily available 2-halo-N-(2-halophenyl)benzamides and amines as the starting materials, and the corresponding 2-aminoarylbenzoxazoles were obtained in good to excellent yields. Both aromatic and aliphatic amines were tolerated, and no ligand was used in this reaction. Gram-scale synthesis was also carried out successfully. These results showed the potential synthetic value of this new reaction in organic synthesis. (C) 2020 Elsevier Ltd. All rights reserved.
Reference of 352-34-1, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 352-34-1.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem