Day: April 1, 2022

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole(SMILESS: FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1,cas:503538-69-0) is researched.Formula: C12H9NO2. The article 《Palladium-Catalyzed Asymmetric Intramolecular Reductive Heck Desymmetrization of Cyclopentenes: Access to Chiral Bicyclo[3.2.1]octanes》 in relation to this compound, is published in Angewandte Chemie, International Edition. Let’s take a look at the latest research on this compound (cas:503538-69-0).

A palladium-catalyzed asym. reductive Heck reaction of unactivated aliphatic alkenes, with eliminable β-hydrogen atoms, was realized for the first time. A series of optically active bicyclo[3.2.1]octanes bearing chiral quaternary and tertiary carbon stereocenters were obtained in good yields with excellent enantioselectivities, exhibited good functional-group tolerance and scalability. Moreover, deuterated optically active bicyclo[3.2.1]octanes were also obtained in high efficiency.

There is still a lot of research devoted to this compound(SMILES：FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1)Application of 503538-69-0, and with the development of science, more effects of this compound(503538-69-0) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 503538-69-0, is researched, Molecular C38H24F4O4P2, about Catalytic Enantioselective Double Carbopalladation/C-H Functionalization with Statistical Amplification of Product Enantiopurity: A Convertible Linker Approach, the main research direction is methacrylamide iodophenyl methyl oxadiazole palladium dimerization catalyst; oxadiazole bis dimethylindolinone stereoselective preparation; C−H activation; asymmetric synthesis; heterocycles; homogeneous catalyst; palladium.Related Products of 503538-69-0.

Combining a catalytic enantioselective reaction with dimerization in a single operation is an efficient way to upgrade the enantiomeric excesses (ee) of the product. Palladium-catalyzed reaction of N-(2-iodophenyl)-N-Me methacrylamide derivatives with oxadiazole afforded, by a double enantioselective carbopalladation/intermol. heteroarene C-H alkylation sequence, homodimers I (R1 = H, 5-OMe, 5-Cl, 6-Cl, etc.; R2 = Me, Bn, i-Pr, etc.) in good yields with excellent ee values. The dimer was subsequently elaborated to the monomer in which the linker (oxadiazole) was incorporated into the target product.

There is still a lot of research devoted to this compound(SMILES：FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1)Related Products of 503538-69-0, and with the development of science, more effects of this compound(503538-69-0) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ) is researched.Synthetic Route of C8H8N2S.Sorba, Giovanni; Garrone, Adele; Serafino, Anna; Gasco, Alberto; Orsetti, Marco published the article 《Potential histamine H2-receptor antagonists: ranitidine analogs containing 2-amino-5(6)-substituted benzimidazole moieties. (1)》 about this compound( cas:27231-36-3 ) in European Journal of Medicinal Chemistry. Keywords: ranitidine analog preparation antihistaminic; aminobenzimidazole preparation antihistaminic; structure antihistaminic activity aminobenzimidazole. Let’s learn more about this compound (cas:27231-36-3).

A series of ranitidine analogs (I: R = H, Me, OMe, Cl, CONH2, CN, and NO2) were synthesized and tested for its in vitro H2-antagonism by using the histamine induced guinea pig atria chronotropic response. These substances generally display good H2-antagonist activity. Some considerations of the structure relationships are also discussed, in particular the physicochem. properties of the benzimidazole moiety.

There is still a lot of research devoted to this compound(SMILES：SC1=NC2=CC(C)=CC=C2N1)Synthetic Route of C8H8N2S, and with the development of science, more effects of this compound(27231-36-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Application of 6797-13-3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Tungstate sulfuric acid as an efficient catalyst for the synthesis of benzoxazoles and benzothiazoles under solvent-free conditions. Author is Farahi, Mahnaz; Karami, Bahador; Azari, Masume.

Tungstate sulfuric acid (TSA) was found to be an efficient and reusable catalyst for the synthesis of benzoxazole and benzothiazole derivatives via reactions of ortho esters with o-aminophenols or o-aminothiophenols in high yields.

There is still a lot of research devoted to this compound(SMILES：CCC1=NC2=CC=CC=C2O1)Application of 6797-13-3, and with the development of science, more effects of this compound(6797-13-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, is researched, Molecular C38H24F4O4P2, CAS is 503538-69-0, about Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems, the main research direction is quinoline asym hydrogenation recyclable iridium catalyst; tetrahydroquinoline alkyl asym synthesis.Reference of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

The iridium complex-catalyzed asym. hydrogenation of quinolines in a poly(ethylene glycol) di-Me ether (DMPEG)/hexane biphasic system was studied. Catalysts with C2-sym. ligands such as Xyl-P-Phos, Cl-MeO-BIPHEP, SYNPHOS, and DifluorPhos are highly effective for this type of reaction. Most of the catalysts tested can be retained in DMPEG (Mn = 500), and the asym. hydrogenation of various quinoline substrates can be carried out in DMPEG/hexane biphasic system with up to 92% ee. The catalysts and the products can be separated via simple phase separation, and the reactivity/stereoselectivity of the catalysts can be retained for at least three reaction cycles.

There is still a lot of research devoted to this compound(SMILES：FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1)Reference of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and with the development of science, more effects of this compound(503538-69-0) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

COA of Formula: C9H9NO. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Reaction of benzoxa(thia)zoles with allenylmagnesium bromide. Synthesis of propargylbenzothiazolines and dipropargylalkyl-o-aminophenols. Author is Babudri, F.; Florio, S..

Benzoxazoles I (R = H, alkyl, CH2Ph; X = O) and benzothiazole I (R = H; X = S) react with H2C:C:CHMgBr (II) (prepared from propargyl bromide) to give 2-HOC6H4NHC(CH2CCH)2R and disulfide III resp. The reaction of I (R = alkyl, CH2Ph; X = S) with II gives the propargylbenzothiazolines IV and I (R = OMe; X = S) produces I (R = CH:C:CH2; X = S).

There is still a lot of research devoted to this compound(SMILES：CCC1=NC2=CC=CC=C2O1)COA of Formula: C9H9NO, and with the development of science, more effects of this compound(6797-13-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(Furan-2-yl)propan-1-one(SMILESS: O=C(C1=CC=CO1)CC,cas:3194-15-8) is researched.Reference of (R)-Piperidin-3-ol hydrochloride. The article 《Hydrothermal formation of hydroxylated benzenes from furan derivatives》 in relation to this compound, is published in Journal of Analytical and Applied Pyrolysis. Let’s take a look at the latest research on this compound (cas:3194-15-8).

Several furan derivatives were subjected to hydrothermolysis at 340° and 27.5 MPa for 1-33 min in a flow system to study their conversion to hydroxylated benzenes. Hydrothermolysis of 0.05M aqueous 5-methyl-2-furaldehyde, 2-acetylfuran and 2-propionylfuran gave 1,4-benzenediol, 1,2-benzenediol and 3-methyl-1,2-benzenediol, resp., with selectivities ranging from 10-65%. Hydrothermolysis of 0.01M aqueous 2-acetyl-5-(hydroxymethyl)furan and 5-(1-hydroxyethyl)-2-furaldehyde did not produce the expected benzenetriols; instead, 2-methyl-1,4-benzenediol could be identified as a product. Hydrothermolysis of 2-vinylfuran did not produce any phenol, an indication that the formation of benzene rings from furans is not accomplished by electrocyclic ring closure. 2,6-Dimethyl-γ-pyrone, a compound that is known to produce 5-methyl-1,3-benzenediol via an aldol condensation under alk. conditions, also gave this product under hydrothermal conditions. A reaction pathway for the hydrothermal formation of hydroxylated benzenes from furan derivatives is presented which is based on C ring formation via an intramol. aldol condensation.

There is still a lot of research devoted to this compound(SMILES：O=C(C1=CC=CO1)CC)Quality Control of 1-(Furan-2-yl)propan-1-one, and with the development of science, more effects of this compound(3194-15-8) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Name: 2-Mercapto-5-methylbenzimidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Strong intra- and intermolecular aurophilic interactions in a new series of brilliantly luminescent dinuclear cationic and neutral Au(I) benzimidazolethiolate complexes. Author is Schneider, Jacob; Lee, Young-A.; Perez, Javier; Brennessel, William W.; Flaschenriem, Christine; Eisenberg, Richard.

The structural and photophys. properties of a new series of cationic and neutral Au(I) dinuclear compounds bridged by bis(diphenylphosphino)methane (dppm) and 5-X-substituted benzimidazolethiolate (X-BIT) ligands, where X = H (a), Me (b), OMe (c), and Cl (d), have been studied. Monocationic complexes [Au2(μ-X-BIT)(μ-dppm)](CF3CO2) (1) were prepared by the reaction of [Au2(μ-dppm)](CF3CO2)2 with 1 equiv of X-BIT in excellent yields. The cations 1a-1d possess similar mol. structures, each with a linear coordination geometry around the Au(I) nuclei, as well as relatively short intramol. Au(I)···Au(I) separations ranging between 2.88907(6) Å for 1d and 2.90607(16) Å for 1a indicative of strong aurophilic interactions. The cations are violet luminescent in CH2Cl2 solution with a λemmax of ca. 365 nm, assigned as ligand-based or metal-centered (MC) transitions. Three of the cationic complexes, 1a, 1b and 1d, exhibit unusual luminescence tribochromism in the solid-state, in which the photoemission is shifted significantly to higher energy upon gentle grinding of microcrystalline samples with ΔE = 1130 cm-1 for 1a, 670 cm-1 (1b), and 870 cm-1 (1d). The neutral dinuclear complexes [Au2(μ-X-BIT)(μ-dppm)] (2a-2d) were formed in good yields by the treatment of a CH2Cl2 solution of cationic compounds 1a-1d with NEt3. Complexes 2a-2d aggregate to form dimers having substantial intra- and intermol. aurophilic interactions with unsupported Au(I)···Au(I) intermol. distances in the range of 2.8793(4)-2.9822(8) Å, compared with intramol. bridge-supported separations of 2.8597(3)-2.9162(3) Å. Complexes 2a-2d exhibit brilliant luminescence in the solid-state and in DMSO solution with red-shifted λemmax energies in the range of 485-545 nm that are dependent on X-BIT and assigned as ligand-to-metal-metal charge transfer (LMCT) states based in part on the extended Au···Au interactions.

There is still a lot of research devoted to this compound(SMILES：SC1=NC2=CC(C)=CC=C2N1)Name: 2-Mercapto-5-methylbenzimidazole, and with the development of science, more effects of this compound(27231-36-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

COA of Formula: C8H8N2S. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about New accelerator-cum-antioxidants for chloroprene rubber. Author is Khanra, Tapan Kumar; Maiti, Sukumar; Adhikari, Basudam.

2-Mercaptoimidazole (MI), N-methyl-2-mercaptoimidazole (MMI), 2-mercaptobenzimidazole (MBI), 5-methyl-2-mercaptobenzimidazole (MMBI) and 5-nitro-2-mercaptobenzimidazole (NMBI) have been tried as the crosslinking agent for chloroprene rubber (Neoprene W). Apart from the curing ability, these imidazole derivatives have also shown antioxidant properties. 1-(N-oxydiethylene thiocarbamyl)-2-(N-oxydiethylene thio)benzimidazole (MBSPT), a novel dual function accelerator-cum-antioxidant for diene rubbers, has also been used in Neoprene W. The cure characteristics, phys. properties of the vulcanizates and their aging behavior of stocks containing these imidazole derivatives, ethylene thiourea (Na-22) and MBSPT have been compared. Some of the compounds viz. MBSPT, MBI and MI may be prescribed as secondary accelerator-cum-antioxidants with some primary accelerator for filled neoprene rubber.

There is still a lot of research devoted to this compound(SMILES：SC1=NC2=CC(C)=CC=C2N1)COA of Formula: C8H8N2S, and with the development of science, more effects of this compound(27231-36-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Pyrolysis of carbohydrates. Analysis of industrial caramel vapors, published in 1989-08-31, which mentions a compound: 3194-15-8, mainly applied to carbohydrate caramelization gas composition; glucose pyrolysis gas composition; sucrose pyrolysis gas composition, Safety of 1-(Furan-2-yl)propan-1-one.

Twenty nine compounds were identified by gas chromatog./mass spectrometry in the gaseous products from pyrolysis of glucose and sucrose under conditions of caramel manufacture The main product was 5-hydroxymethylfurfural (70-90%, depending on pyrolysis conditions). The compound was formed more easily from sucrose than from glucose, and its yield increased with increasing pyrolysis temperature Aliphatic and keto acids, heterocyclic compounds with furan or pyran ring, aromatic compounds, and bisfuran compounds were formed in minor amounts

There is still a lot of research devoted to this compound(SMILES：O=C(C1=CC=CO1)CC)Safety of 1-(Furan-2-yl)propan-1-one, and with the development of science, more effects of this compound(3194-15-8) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem