Month: April 2022

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Cho, Chang-Woo; Krische, Michael J. researched the compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole( cas:503538-69-0 ).Computed Properties of C38H24F4O4P2.They published the article 《α-Hydroxy Esters via Enantioselective Hydrogen-Mediated C-C Coupling: Regiocontrolled Reactions of Silyl-Substituted 1,3-Diynes》 about this compound( cas:503538-69-0 ) in Organic Letters. Keywords: ester hydroxy preparation asym regioselective reductive coupling alkadiyne glyoxylate; coupling asym reductive alkadiyne oxo ester rhodium diphosphine catalyzed; enynoate hydroxy preparation asym regioselective coupling alkadiyne glyoxylate. We’ll tell you more about this compound (cas:503538-69-0).

Rhodium-catalyzed asym. reductive coupling of Et glyoxalate and 1,3-diynes in the presence of mol. hydrogen afforded α-hydroxy-β,γ-enynoates with high regio- and enantioselectivity. Reaction of R1CCCCR3 with OHCCOOR2 and H2 in the presence of Rh-(R)-Cl,MeO-BIPHEP [(1R)-5,5′-dichloro-6,6′-dimethoxy-1,1′-biphenyl-2,2′-bis(diphenylphosphine)] gave (2R)-R3CCCH:CR1CH(OH)COOR2 (1c, R1 = R3 = Ph, R2 = Et; 4c-9c, R1 = Me3Si, Me2tBuSi; R2 = Et; R3 = Ph, Me, cyclopropylmethyl, Me2tBuSiOCH2) with alkyne regioselectivity of >99% and ee values of 89-94%. Notably, for trialkylsilyl-substituted 1,3-diynes, C-C coupling occurs exclusively at the carbon atom bearing silyl group. π-Back-bonding from low valent rhodium as described by the Dewar-Chatt-Duncanson model appears to direct the regiochem. of C-C coupling, as corroborated by calculations of the diyne LUMO coefficients

In addition to the literature in the link below, there is a lot of literature about this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Computed Properties of C38H24F4O4P2, illustrating the importance and wide applicability of this compound(503538-69-0).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A One-Step Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Esters from o-Nitrobenzaldehydes, published in 2010-05-21, which mentions a compound: 481054-89-1, mainly applied to nitrobenzaldehyde diethoxypropionic acid ester modified reductive Friedlaender reaction tin; quinolinecarboxylic acid ester preparation; tin chloride modified reductive Friedlaender reaction mediator, COA of Formula: C12H10BrNO2.

A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid Et esters, e.g., I (R1 = Me, Et; R2 = H, F, Cl, Br, OH), is described. The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inexpensive, com. available 3,3-diethoxypropionic acid Et ester and SnCl2·2H2O in refluxing ethanol.

In addition to the literature in the link below, there is a lot of literature about this compound(Ethyl 6-bromoquinoline-3-carboxylate)COA of Formula: C12H10BrNO2, illustrating the importance and wide applicability of this compound(481054-89-1).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Recommanded Product: 33941-15-0. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1,4,7,10,13-Pentaoxa-16-azacyclooctadecane, is researched, Molecular C12H25NO5, CAS is 33941-15-0, about Facile fabrication of crown ether functionalized lignin-based biosorbent for the selective removal of Pb(II). Author is Jin, Can; Liu, Guifeng; Wu, Guomin; Huo, Shuping; Liu, Zengshe; Kong, Zhenwu.

A novel 1-Aza-18-crown-6 functionalized lignin-based adsorbent (AFL) is facilely prepared through Mannich reaction in a one-step process. Structure characterization by Fourier transform IR spectroscopy, NMR spectroscopy, elemental anal. and XPS confirmed the successful fabrication of AFL. AFL was observed to display enhanced adsorption capacity (Qmax = 91.4 mg/g) and superior selectivity toward Pb(II) ions, due to a display of crown ether units and their interaction with metal ions. The adsorption equilibrium results from a kinetic study indicated that the Pb(II) adsorption by AFL was a chemisorption process. Addnl., the obtained thermodn. parameters showed the adsorption mechanism to be an exothermic and spontaneous process at room temperature The AFL could be regenerated by desorption of Pb(II) ions and remained at over 80% adsorption efficiency after four adsorption-desorption cycles. Therefore, the AFL displays acceptable adsorption performance and can serve as a bioresource-based and recyclable adsorbent material, portending a new expectation in the application for water purification engineering.

In addition to the literature in the link below, there is a lot of literature about this compound(1,4,7,10,13-Pentaoxa-16-azacyclooctadecane)Recommanded Product: 33941-15-0, illustrating the importance and wide applicability of this compound(33941-15-0).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Conformational studies by dynamic nuclear magnetic resonance. Part 30. Exchange kinetics between the rotamers of 2-acylfurans and -thiophenes, the main research direction is rotation barrier acylfuran acylthiophene; acylfuran rotation barrier NMR; acylthiophene rotation barrier NMR; conformation acylfuran acylthiophene NMR; furan acyl conformation NMR; thiophene acyl conformation NMR.Recommanded Product: 1-(Furan-2-yl)propan-1-one.

Low-temperature 13C NMR spectra showed 2 different groups of signals, corresponding to the O,O-anti- and O,O-syn-rotamers, of 2-acylfurans I (X = O; R = H, Me, Et, CHMe2, CHEt2, CMe3). The ratios of these rotamers in Me2O were obtained; barriers for the syn-anti interconversion decrease with the increasing bulkiness of R. Although sep. 13C signals could not be detected for the rotamers of the corresponding 2-acylthiophenes I; (X = S, R = as before), line-broadening effects nonetheless allowed measurement of the interconversion barriers. Lanthanide-induced shift experiments carried out on the latter derivatives (at both 1H and 13C frequencies) showed that in all the 2-acylthiophenes investigated, the S,O-syn rotamers are predominant.

In addition to the literature in the link below, there is a lot of literature about this compound(1-(Furan-2-yl)propan-1-one)Recommanded Product: 1-(Furan-2-yl)propan-1-one, illustrating the importance and wide applicability of this compound(3194-15-8).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors, the main research direction is mercaptobenzimidazole benzyl alc etherification; benzimidazole thioether preparation cyclooxygenase inhibitor; mercaptobenzothiazole benzyl alc etherification; benzothiazole thioether preparation cyclooxygenase inhibitor; mercaptobenzoxazole benzyl alc etherification; benzoxazole thioether preparation cyclooxygenase inhibitor.SDS of cas: 27231-36-3.

A series of 2-[[(2-alkoxy-6-pentadecylphenyl)methyl]thio]-1H-benzimidazoles, benzothiazoles and benzoxazoles have been prepared from anacardic acid and their ability to inhibit human cyclooxygenase-2 enzyme (COX-2) investigated. The active compounds were screened for cyclooxygenase-1 (COX-1) inhibition. I (X = NH; R1 = H; R2 = OMe) is 384-fold and I (X = S; R1 = Me; R2 = H) is more than 470-fold selective towards COX-2 compared to COX-1. Thus, this class of compounds may serve as excellent candidates for selective COX-2 inhibition.

In addition to the literature in the link below, there is a lot of literature about this compound(2-Mercapto-5-methylbenzimidazole)SDS of cas: 27231-36-3, illustrating the importance and wide applicability of this compound(27231-36-3).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Related Products of 6797-13-3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Ruthenium-Catalyzed Synthesis of Benzoxazoles Using Acceptorless Dehydrogenative Coupling Reaction of Primary Alcohols with 2-Aminophenol under Heterogeneous Conditions. Author is Khalafi-Nezhad, Ali; Panahi, Farhad.

An efficient ruthenium-catalyzed acceptorless dehydrogenative coupling reaction of primary alcs. with 2-aminophenol for one-pot synthesis of benzoxazoles e. g., I, is introduced. The phosphine-functionalized magnetic nanoparticles (PFMNPs; Fe3O4@SiO2@PPh2) as a magnetic recyclable phosphorus ligand in the presence of Ru2Cl4(CO)6 was found to be an efficient heterogeneous catalytic system for promotion of the designed protocol. The reaction was carried out efficiently with a variety of substrates to give the corresponding products in moderate to good yields.

In addition to the literature in the link below, there is a lot of literature about this compound(2-Ethylbenzo[d]oxazole)Related Products of 6797-13-3, illustrating the importance and wide applicability of this compound(6797-13-3).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Ames, Jennifer M.; Guy, Robin C. E.; Kipping, Gary J. published the article 《Effect of pH, Temperature, and Moisture on the Formation of Volatile Compounds in Glycine/Glucose Model Systems》. Keywords: glycine glucose aroma compound Maillard reaction; extrusion cooking glycine glucose Maillard reaction.They researched the compound: 1-(Furan-2-yl)propan-1-one( cas:3194-15-8 ).Name: 1-(Furan-2-yl)propan-1-one. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:3194-15-8) here.

Mixtures of glycine, glucose, and starch were extrusion cooked using sodium hydroxide at 0, 3, and 6 g/L of extruder water feed, 18% moisture, and 120, 150, and 180 °C target die temperatures, giving extrudates with pH values of 5.6, 6.8, and 7.4. Freeze-dried equimolar solutions of glucose and glycine were heated either dry or after equilibration to ∼13% moisture at 180°C in a reaction-tube system designed to mimic the heating profile in an extruder. Volatile compounds were isolated onto Tenax and analyzed by gas chromatog.-mass spectrometry. For the extrudates, total yields of volatiles increased with decreasing pH at 180°C, reached a maximum at pH 6.8 at 150°C, and increased with increasing pH at 120°C. Amounts increased with temperature at all pH values. Pyrazines were the most abundant class for all sets of conditions (54-79% of total volatiles). Pyrroles, ketones, furans, oxazoles, and pyridines were also identified. Yields of volatiles from the reaction-tube samples increased by >60% in the moist system. Levels of individual classes also increased in the presence of moisture, except pyrazines, which decreased ∼3.5-fold. Twenty-one of the compounds were common to the reaction-tube samples and the extrudates.

In addition to the literature in the link below, there is a lot of literature about this compound(1-(Furan-2-yl)propan-1-one)Name: 1-(Furan-2-yl)propan-1-one, illustrating the importance and wide applicability of this compound(3194-15-8).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Mohammadpoor-Baltork, I.; Moghadam, M.; Tangestaninejad, S.; Mirkhani, V.; Zolfigol, M. A.; Hojati, S. F. published the article 《Silica sulfuric acid catalyzed synthesis of benzoxazoles, benzimidazoles and oxazolo[4,5-b]pyridines under heterogeneous and solvent-free conditions》. Keywords: orthoester aminophenol phenylenediamine aminopyridinol cyclization silica sulfuric acid catalyst; benzoxazole preparation orthoester aminophenol cyclization silica sulfuric acid catalyst; benzimidazole preparation orthoester phenylenediamine cyclization silica sulfuric acid catalyst; oxazolopyridine preparation orthoester aminopyridineol cyclization silica sulfuric acid catalyst.They researched the compound: 2-Ethylbenzo[d]oxazole( cas:6797-13-3 ).Synthetic Route of C9H9NO. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:6797-13-3) here.

A simple, rapid and efficient method for the preparation of benzoxazoles, benzimidazoles and oxazolo[4,5-b]pyridines from the reaction of orthoesters with o-aminophenols, o-phenylenediamine and 2-amino-3-hydroxypyridine in the presence of silica sulfuric acid under heterogeneous and solvent-free conditions is reported. The significant features of this method are short reaction times, high yields of the products, mild reaction conditions, solvent free reaction, cheapness, non-toxicity and reusability of the catalyst.

There are many compounds similar to this compound(6797-13-3)Synthetic Route of C9H9NO. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Application of 33941-15-0. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1,4,7,10,13-Pentaoxa-16-azacyclooctadecane, is researched, Molecular C12H25NO5, CAS is 33941-15-0, about Axially- and Meso-Substituted Aza-Crown-Ether-Incorporated BIII Subporphyrins: Control of Electron-Donating Ability by Metal Ion Chelation.

A series of subporphyrin-based fluorescent probes bearing 1-aza-15-crown-5 or 1-aza-18-crown-6 moieties at the meso or axial positions were prepared by Pd-catalyzed Buchwald-Hartwig amination reaction of the corresponding bromosubporphyrins. Both types of aza-crown-ether-incorporated subporphyrins were fluorescent in solution and exhibited cation-dependent absorption and fluorescence changes. In fluorescence titration experiments, opposite responses were observed for the two types of subporphyrins. Namely, fluorescence quenching occurred for the meso-substituted subporphyrins while fluorescence enhancement was observed for the axially-substituted subporphyrins. These results demonstrate the advantage of subporphyrins being viable to serve as turn-off-type or turn-on-type fluorescence probes, depending upon substitution pattern.

There are many compounds similar to this compound(33941-15-0)Application of 33941-15-0. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Recommanded Product: 2-Mercapto-5-methylbenzimidazole. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Microwave-assisted synthesis of 3-[2-(1H-benzimidazol-2-yl-sulfanyl)-acetyl]-chromen-2-ones.

Synthesis of some new 3-[2-(1H-benzimidazol-2-yl-sulfanyl)-acetyl]-chromen-2-ones by treatment of 2-mercaptobenzimidazoles with 3-(2-bromoacetyl)chromen-2-one under microwave irradiation technique was described.

There are many compounds similar to this compound(27231-36-3)Recommanded Product: 2-Mercapto-5-methylbenzimidazole. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem