Day: January 4, 2023

Efficient synthesis of 2-substituted benzoxazoles via Beckmann rearrangement of 2-hydroxyaryl ketoximes using diethyl chlorophosphate was written by Sardarian, A. R.;Shahsavari-Fard, Z.. And the article was included in Synlett in 2008.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

An efficient method for the synthesis of 2-substituted benzoxazoles, e.g., I has been developed using di-Et chlorophosphate. 2-Hydroxyaryl ketoximes, e.g., II are efficiently converted to benzoxazoles by heating in the presence of di-Et chlorophosphate via a Beckmann rearrangement of the corresponding ketoxime in excellent yields. This method avoids the use of strong acids, harsh conditions, and long reaction times. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Platinum(II) complexes based on phenylbenzoazole-derived ligands for phosphorescent organic light-emitting diodes was written by Kang, Soo Kyung;Hwang, Namhee;Pak, Soyoung;Kim, Young Kwan;Yoon, Seung Soo. And the article was included in Journal of Nanoscience and Nanotechnology in 2020.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

Phosphorescent Pt(II) complexes based on phenylbenzoazole ligands were synthesized and their photophys. properties were investigated for OLEDs. Multilayered OLEDs devices using these complexes as emitters showed the efficient emissions, which are very sensitive to the structural and photophys. properties of Pt(II) complexes. In particularly, a device C using Pt(II) complex 2 based on phenylbenzoazole ligand as the dopant exhibited efficient emission with a luminous efficiency, a power efficiency, an external quantum efficiency, and CIE coordinates of 8.03 cd/A, 2.79 Im/W, 4.84% at 20 mA/cm2, and (0.63, 0.35) at 10.0 V, resp. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Iron(III) complexes with benzoxazole derivatives was written by Pinna, Rosalba;Ponticelli, Gustavo;Aramu, Francesco;Delunas, Adriano;Maxia, Vera. And the article was included in Transition Metal Chemistry (Dordrecht, Netherlands) in 1988.Related Products of 5676-58-4 This article mentions the following:

FeL_nX₃·mH₂O (L = benzoxazole, 2-methylbenzoxazole, 2,5-dimethylbenzoxazole (2,5-diMebenzox); n = 2, 3, 4, 6; X = Cl, Br, NO₃ or ClO₄; m = 0, 1, 2, 5) were prepared and studied by chem. anal., magnetic moments, IR, electronic, Moessbauer spectra and molar conductivity values. The oxazoles are N_ring bonded and the complexes are hexacoordinate in the solid state with exception of 5-coordinate Fe(2,5-diMebenzox)₂Br₃. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Copper-Containing Polyoxometalate-Based Metal-Organic Frameworks as Heterogeneous Catalysts for the Synthesis of N-Heterocycles was written by Li, Ke;Liu, Yu-Feng;Lin, Xiao-Ling;Yang, Guo-Ping. And the article was included in Inorganic Chemistry in 2022.HPLC of Formula: 5676-58-4 This article mentions the following:

Three new polyoxometalate-based metal-organic frameworks (POMOFs) [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₅(SiW₁₂O₄₀)_0.5](H₂SiW₁₂O₄₀)_0.5·2.5H₂O (CuSiW), [Cu₃(μ₃-OH)(tba)₃(Htba)(H₂O)₂(HPMo₁₂O₄₀)]·7H₂O (CuPMo), and [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₃(PW₁₂O₄₀)_0.5]₂(PW₁₂O₄₀)·0.5H₂O (CuPW) were constructed using multinuclear copper clusters, 3-(4H-1,2,4-triazol-4-yl)benzoic acid (Htba), and Keggin polyoxometalates (POMs). Different POMs regulate the formation of different multinuclear copper clusters (“boat” tetranuclear clusters in CuSiW, trinuclear clusters in CuPMo, and “chair” tetranuclear clusters in CuPW) and different topol. structures of CuSiW, CuPMo, and CuPW (3-connected two-dimensional (2D) network for CuSiW, 4-connected 2D network for CuPMo, and (4,6)-connected three-dimensional network for CuPW). CuSiW, CuPMo, and CuPW as heterogeneous catalysts combine the high stability of MOFs in polar solvents and excellent catalytic activity of POMs and could be used for the synthesis of nitrogen-heterocycle compounds The condensation cyclization reactions of 2-aminophenols/benzenesulfonyl hydrazines with 1,3-diketones produce benzoazoles and pyrazoles in good to excellent yields under the catalysis of CuPMo. Moreover, the catalyst could be reused at least for 7 runs, and this protocol was suitable for gram-scale reactions. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

An efficient synthesis of 2-substituted benzoxazoles via RuCl₃.3H₂O catalyzed tandem reactions in ionic liquid was written by Fan, Xuesen;He, Yan;Wang, Yangyang;Zhang, Xinying;Wang, Jianji. And the article was included in Chinese Journal of Chemistry in 2011.Reference of 99586-31-9 This article mentions the following:

An efficient synthesis of 2-substituted benzoxazoles through RuCl₃.3H₂O-catalyzed, air-oxidized tandem reactions of 2-aminophenols and aldehydes in [bmim]BF₄ was developed. This synthetic strategy has such advantages as mild reaction conditions, cost-free oxidant, readily available starting materials, and recyclable catalyst and solvent. It was successfully used in the synthesis of new 5-(benzoxazol-2-yl)-2′-deoxyuridines. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Reference of 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Reference of 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem