Day: January 6, 2023

Absorption and fluorescence characteristics of some 2-alkyl- and 2-arylbenzoxazoles in different solvents and at various acid concentrations was written by Dey, Joy Krishna;Dogra, Sneh K.. And the article was included in Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical in 1990.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

Absorption and fluorescence spectral characteristics of some 2-alkyl- and 2-arylbenzoxazoles have been studied in different solvents and at various acid concentrations Dual fluorescence observed in the monocations of 2-alkylbenzoxazoles is due to π^* → π and charge transfer (CT) transitions, indicating the near degeneracy of excited single states. 2-Arylbenzoxazoles and the corresponding monocations exhibit only a single fluorescence band due to π^* → π transition. PK_a values for the monocation-neutral equilibrium in both S₀ and S₁ states of the mols. have been determined PPP method for all the mols. and CNDO/S method for 2-methyl-, and 2-phenylbenzoxazoles have been employed to calculate transition energies, transition polarization and charge densities at different atoms in the S₀ and S₁ states to substantiate exptl. data and, hence, to verify the applicability of the methods for heterocycles containing two hetero atoms. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Although benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

A comparative study of symmetrical and unsymmetrical trimethine cyanine dyes bearing benzoxazolyl and benzothiazolyl groups was written by Shi, Quan-Quan;Sun, Ru;Ge, Jian-Feng;Xu, Qing-Feng;Li, Na-Jun;Lu, Jian-Mei. And the article was included in Dyes and Pigments in 2012.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

Six sym. and unsym. trimethine cyanine dyes bearing benzothiazolyl and benzoxazolyl groups were synthesized. Their linear optical properties were studied. The variation of hetero atoms play an important role in the spectral properties of the dyes. Sequential replacement of the oxygen atom by the sulfur atom resulted in a change in shade from yellow to purple. In order to understand the relation between the mol. structures and the spectral properties of these dyes, theor. calculations were made using the Gaussian program. Key parameters related to absorption and emission spectra were reported and discussed. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Ligand-Free Copper-Catalyzed Synthesis of Substituted Benzimidazoles, 2-Aminobenzimidazoles, 2-Aminobenzothiazoles, and Benzoxazoles was written by Saha, Prasenjit;Ramana, Tamminana;Purkait, Nibadita;Ali, Ashif Md;Paul, Rajesh;Punniyamurthy, Tharmalingam. And the article was included in Journal of Organic Chemistry in 2009.COA of Formula: C13H8BrNO This article mentions the following:

The synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles is described via intramol. cyclization of o-bromoaryl derivatives using copper(II) oxide nanoparticles in DMSO under air. E.g., cyclization of o-bromoaryl amidine I gave 95% benzimidazoles II. The procedure is exptl. simple, general, efficient, and free from addition of external chelating ligands. It is a heterogeneous process and the copper(II) oxide nanoparticles can be recovered and recycled without loss of activity. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9COA of Formula: C13H8BrNO).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.COA of Formula: C13H8BrNO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Silica-sulfuric acid catalyzed microwave-assisted synthesis of substituted benzoxazoles and their antimicrobial activity was written by Anand, M.;Ranjitha, A.;Himaja, M.. And the article was included in International Research Journal of Pharmacy in 2011.COA of Formula: C9H9NO This article mentions the following:

Benzoxazole derivatives were designed for a study of their biol. activity, the synthesis of the target compounds was achieved by a microwave-mediated method using sulfated silica (solid acid) as catalyst and ortho esters and 2-aminophenol derivatives as starting materials and the products thus obtained were confirmed by ¹H-NMR and MS. The title compounds were screened against Staphylococcus aureus, Escherichia coli, Candida albicans and Candida glabrata (yeast) and it was discovered that these compounds displayed antimicrobial activity in comparison with Trimethoprim and Miconazole. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4COA of Formula: C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.COA of Formula: C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Application of nano SnO₂ as a green and recyclable catalyst for the synthesis of 2-aryl or alkylbenzoxazole derivatives under ambient temperature was written by Vahdat, Seyed Mohammad;Raz, Shima Ghafouri;Baghery, Saeed. And the article was included in Journal of Chemical Sciences (Bangalore, India) in 2014.Synthetic Route of C9H9NO This article mentions the following:

Application of nano-SnO₂ as an efficient and environmentally benign catalyst was explored for the synthesis of 2-arylbenzoxalzole derivatives I [R = Ph, 2-HOC₆H₄, 2-MeOC₆H₄, 2-furyl, 3-Cl, 2-thienyl, etc., R¹ = H, Me, Cl, NO₂] or 2-alkylbenzoxazole derivatives I [R = H, Me, Et, R¹ = H, Me, Cl] via condensation reaction of 2-aminophenols with aryl aldehydes or orthoesters, resp. The SnO₂ nanocatalyst is reusable, cheap and eco-friendly. This catalyst offers several advantages including mild reaction conditions, high yield of products, lower catalyst loading and shorter reaction times with simple exptl. and isolation procedures. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Synthetic Route of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Synthetic Route of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem