Month: January 2023

Synthesis and optical properties of some E,E-1,4-bis-[2′,2”-(benzoxazolylethenyl)]benzene and its substituted derivatives was written by Zhou, Yimin;Wu, Yanmin;Gao, Zhenheng. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 1989.Electric Literature of C9H9NO This article mentions the following:

The title compounds I (R and R¹ = H, halo, alkyl, Ph) were prepared by condensation of 1,4-diformylbenzene with 2-methylbenzoxazoles. IR, NMR, UV, fluorescence spectra as well as laser properties of I were reported. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Thallium in organic synthesis. 65. A novel synthesis of benzoxazoles from anilides was written by Taylor, Edward C.;Katz, Alan H.;Alvarado, Sergio I.;McKillop, Alexander. And the article was included in Journal of Organic Chemistry in 1986.HPLC of Formula: 5676-58-4 This article mentions the following:

Benzoxazoles I (R = Me, Ph, 4-ClC₆H₄; R¹ = H, Me, CHMeCO₂Me; R² = H, Me) are readily formed by photolysis of the regiospecifically ortho-thallated anilides II. This new methodol. was used for a synthesis of benoxaprofen (I, R = 4-ClC₆H₄, R¹ = CHMeCO₂H, R² = H) which exploits a second thallium-mediated reaction of 3-EtCOC₆H₄NHCOC₆H₄Cl-4 with HC(OMe)₃ for generation of the α-methylacetic acid substituent. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Reactions of phosphorus compounds. 36. Heterocyclic synthesis via methylenetriphenylphosphorane extrusion was written by Schweizer, Edward E.;DeVoe, Susan V.. And the article was included in Journal of Organic Chemistry in 1975.Reference of 5676-58-4 This article mentions the following:

Addnl. data considered in abstracting and indexing are available from a source cited in the original document. A novel ylide elimination reaction gave 2-methylbenzothiazole (I), 2-methylquinazol-4-one (II), and 2,5-dimethylbenzoxazole (III) in greater than 62% yield. IV, V, and VI reacted with HCCCH2PPh3Br via the corresponding VII to give I, II, and III. The ylide formed from IV was not isolated. The reaction is a general heterocyclic synthesis. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Reference of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Reference of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Lewis-Acid-Mediated Benzotriazole Ring Cleavage (BtRC) Strategy for the Synthesis of 2-Aryl Benzoxazoles from N-Acylbenzotriazoles was written by Singh, Anoop S.;Mishra, Nidhi;Kumar, Dhananjay;Tiwari, Vinod K.. And the article was included in ACS Omega in 2017.HPLC of Formula: 99586-31-9 This article mentions the following:

A Lewis-acid-mediated ring cleavage of acylbenzotriazoles (RCOBt) followed by cyclization to corresponding benzoxazoles was achieved in good to excellent yields. The reaction was found consistent with the milligram to gram scale. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9HPLC of Formula: 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.HPLC of Formula: 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Efficient synthesis of 2-substituted benzoxazoles via Beckmann rearrangement of 2-hydroxyaryl ketoximes using diethyl chlorophosphate was written by Sardarian, A. R.;Shahsavari-Fard, Z.. And the article was included in Synlett in 2008.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

An efficient method for the synthesis of 2-substituted benzoxazoles, e.g., I has been developed using di-Et chlorophosphate. 2-Hydroxyaryl ketoximes, e.g., II are efficiently converted to benzoxazoles by heating in the presence of di-Et chlorophosphate via a Beckmann rearrangement of the corresponding ketoxime in excellent yields. This method avoids the use of strong acids, harsh conditions, and long reaction times. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Platinum(II) complexes based on phenylbenzoazole-derived ligands for phosphorescent organic light-emitting diodes was written by Kang, Soo Kyung;Hwang, Namhee;Pak, Soyoung;Kim, Young Kwan;Yoon, Seung Soo. And the article was included in Journal of Nanoscience and Nanotechnology in 2020.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

Phosphorescent Pt(II) complexes based on phenylbenzoazole ligands were synthesized and their photophys. properties were investigated for OLEDs. Multilayered OLEDs devices using these complexes as emitters showed the efficient emissions, which are very sensitive to the structural and photophys. properties of Pt(II) complexes. In particularly, a device C using Pt(II) complex 2 based on phenylbenzoazole ligand as the dopant exhibited efficient emission with a luminous efficiency, a power efficiency, an external quantum efficiency, and CIE coordinates of 8.03 cd/A, 2.79 Im/W, 4.84% at 20 mA/cm2, and (0.63, 0.35) at 10.0 V, resp. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Iron(III) complexes with benzoxazole derivatives was written by Pinna, Rosalba;Ponticelli, Gustavo;Aramu, Francesco;Delunas, Adriano;Maxia, Vera. And the article was included in Transition Metal Chemistry (Dordrecht, Netherlands) in 1988.Related Products of 5676-58-4 This article mentions the following:

FeL_nX₃·mH₂O (L = benzoxazole, 2-methylbenzoxazole, 2,5-dimethylbenzoxazole (2,5-diMebenzox); n = 2, 3, 4, 6; X = Cl, Br, NO₃ or ClO₄; m = 0, 1, 2, 5) were prepared and studied by chem. anal., magnetic moments, IR, electronic, Moessbauer spectra and molar conductivity values. The oxazoles are N_ring bonded and the complexes are hexacoordinate in the solid state with exception of 5-coordinate Fe(2,5-diMebenzox)₂Br₃. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Copper-Containing Polyoxometalate-Based Metal-Organic Frameworks as Heterogeneous Catalysts for the Synthesis of N-Heterocycles was written by Li, Ke;Liu, Yu-Feng;Lin, Xiao-Ling;Yang, Guo-Ping. And the article was included in Inorganic Chemistry in 2022.HPLC of Formula: 5676-58-4 This article mentions the following:

Three new polyoxometalate-based metal-organic frameworks (POMOFs) [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₅(SiW₁₂O₄₀)_0.5](H₂SiW₁₂O₄₀)_0.5·2.5H₂O (CuSiW), [Cu₃(μ₃-OH)(tba)₃(Htba)(H₂O)₂(HPMo₁₂O₄₀)]·7H₂O (CuPMo), and [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₃(PW₁₂O₄₀)_0.5]₂(PW₁₂O₄₀)·0.5H₂O (CuPW) were constructed using multinuclear copper clusters, 3-(4H-1,2,4-triazol-4-yl)benzoic acid (Htba), and Keggin polyoxometalates (POMs). Different POMs regulate the formation of different multinuclear copper clusters (“boat” tetranuclear clusters in CuSiW, trinuclear clusters in CuPMo, and “chair” tetranuclear clusters in CuPW) and different topol. structures of CuSiW, CuPMo, and CuPW (3-connected two-dimensional (2D) network for CuSiW, 4-connected 2D network for CuPMo, and (4,6)-connected three-dimensional network for CuPW). CuSiW, CuPMo, and CuPW as heterogeneous catalysts combine the high stability of MOFs in polar solvents and excellent catalytic activity of POMs and could be used for the synthesis of nitrogen-heterocycle compounds The condensation cyclization reactions of 2-aminophenols/benzenesulfonyl hydrazines with 1,3-diketones produce benzoazoles and pyrazoles in good to excellent yields under the catalysis of CuPMo. Moreover, the catalyst could be reused at least for 7 runs, and this protocol was suitable for gram-scale reactions. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

An efficient synthesis of 2-substituted benzoxazoles via RuCl₃.3H₂O catalyzed tandem reactions in ionic liquid was written by Fan, Xuesen;He, Yan;Wang, Yangyang;Zhang, Xinying;Wang, Jianji. And the article was included in Chinese Journal of Chemistry in 2011.Reference of 99586-31-9 This article mentions the following:

An efficient synthesis of 2-substituted benzoxazoles through RuCl₃.3H₂O-catalyzed, air-oxidized tandem reactions of 2-aminophenols and aldehydes in [bmim]BF₄ was developed. This synthetic strategy has such advantages as mild reaction conditions, cost-free oxidant, readily available starting materials, and recyclable catalyst and solvent. It was successfully used in the synthesis of new 5-(benzoxazol-2-yl)-2′-deoxyuridines. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Reference of 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Reference of 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem