Day: February 22, 2023

Palladium-catalyzed trisallylation of benzoxazoles and 2-aryl-1,3,4-oxadiazoles with alkyne was written by Zheng, Jun;Hosseini-Eshbala, Fereshteh;Dong, Ya-Xi;Breit, Bernhard. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Recommanded Product: 132227-03-3 This article mentions the following:

A Pd-catalyzed direct C-H trisallylation of azoles with alkyne has been described. A consecutive C(sp²)-H allylation/olefin isomerization/double C(sp³)-H allylation of azoles and alkyne via a palladium catalysis system proceeds efficiently to afford the corresponding C2-alkenylated azoles containing an all quaternary carbon center. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Recommanded Product: 132227-03-3).

5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Recommanded Product: 132227-03-3

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Abnormal-NHC-Supported Nickel Catalysts for Hydroheteroarylation of Vinylarenes was written by Vijaykumar, Gonela;Jose, Anex;Vardhanapu, Pavan K.;P, Sreejyothi;Mandal, Swadhin K.. And the article was included in Organometallics in 2017.Category: benzoxazole This article mentions the following:

Herein the authors report the hydroheteroarylation of vinylarenes with benzoxazole in the presence of a free abnormal N-heterocyclic carbene and Ni(COD)₂, resulting in 1,1-diarylethane products exclusively. In an attempt to understand the mechanism of this catalytic reaction, two abnormal-NHC (aNHC)-coordinated Ni(II) cyclooctenyl complexes were isolated and their solid-state structures were determined by x-ray crystallog. studies. These Ni(II) cyclooctenyl complexes act as active catalyst precursors to generate in situ aNHC-Ni(0) species, which undergo oxidative addition with heteroarene to form Ni(II) hydride intermediates. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Category: benzoxazole).

5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Category: benzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Mixed N-heterocycles/N-heterocyclic carbene palladium(II) allyl complexes as precatalysts for direct arylation of azoles with aryl bromides was written by Yang, Jin. And the article was included in Tetrahedron in 2019.Computed Properties of C8H7NO2 This article mentions the following:

A series of mixed N-heterocycles/N-heterocyclic carbene palladium(II) allyl complexes with general formula [(NHC)Pd(η³-allyl)]₂(μ₂-N-heterocycles)(BF₄)₂ were prepared in one pot based on anion metathesis of (NHC)Pd(η³-allyl)Cl complexes and then ligand replacement with N-heterocycles [N-heterocycles = pyrazine (pyz), 4,4′-bipyridine (bpy) and trans-4,4′-bipyridylethylene (bpe)]. The solid-state structures showed dinuclear structures with two palladium(II) centers holding together by bridged N-heterocycles. Initially investigation of the obtained complexes as precatalysts for direct C-H bond arylation of azoles with aryl bromides was carried out. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Computed Properties of C8H7NO2).

5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Computed Properties of C8H7NO2

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

TEMPO/PhI(OAc)₂-mediated Direct Sulfoximination of Benzoxazoles under Metal-free Conditions was written by Wang, Jian;Tu, Changqing;Feng, Mei-Lin;Li, Nan. And the article was included in Chemistry Letters in 2022.HPLC of Formula: 132227-03-3 This article mentions the following:

A metal-free reaction system consisting of TEMPO and PhI(OAc)₂ for the oxidative C-N coupling of benzoxazoles with NH-sulfoximines had been developed to obtain arylsulfoximines I [R¹ = H, 5-Cl, 7-Br, etc.; R² = Me, Et, n-Bu, Bn; R³ = Ph, 4-FC₆H₄, 2-BrC₆H₄, etc.]. The reaction could proceed under ambient atm. without any metal catalyst at room temperature to afford the corresponding 2-iminoazoles in moderate to high yields. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3HPLC of Formula: 132227-03-3).

5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.HPLC of Formula: 132227-03-3

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Heteroleptic palladium(II) complexes containing N-heterocyclic carbenes and 4-phenyl-1H-1,2,3-triazole: Synthesis, characterization, and catalytic application was written by Chen, Wei;Yang, Jin. And the article was included in Journal of Coordination Chemistry in 2018.Electric Literature of C8H7NO2 This article mentions the following:

Reaction of the dimeric N-heterocyclic carbene (NHC) palladium compounds [Pd(μ-Cl)(Cl)(NHC)]₂ with 4-phenyl-1H-1,2,3-triazole gave four mono- and dinuclear complexes 1–4. Mononuclear complexes 1 and 2 [(NHC)PdCl₂(4-phenyl-1H-1,2,3-triazole)] were obtained when the reactions were performed in CH₂Cl₂, whereas dinuclear complexes 3 and 4 [Pd₂(μ-Cl)(μ-4-phenyl-1H-1,2,3-triazole)Cl₂(NHC)₂] were obtained when the reactions were performed in THF in reflux with Et₃N as the base. Further explorations of the catalytic properties of for Pd-catalyzed transformations were performed and these complexes exhibited moderate to high catalytic activities for Suzuki-Miyaura coupling and arylation of benzoxazoles with aryl bromides. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Electric Literature of C8H7NO2).

5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Electric Literature of C8H7NO2

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem