Month: February 2023

Cyanine dyes with high absorption cross section as donor chromophores in energy transfer primers was written by Hung, Su-Chun;Ju, Jingyue;Mathies, Richard A.;Glazer, Alexander N.. And the article was included in Analytical Biochemistry in 1996.Related Products of 5676-58-4 This article mentions the following:

Energy transfer (ET) fluorescent primers are significantly superior to single dye-labeled primers for DNA sequencing and multiplex genetic analyses (Ju, J. et al., 1996). We describe here ET primers in which a donor chromophore with a large absorption cross section but a low fluorescence quantum yield is exploited to increase the Stokes-shifted fluorescence emission of acceptor dyes. The new ET primers have 3-(ε-carboxypentyl)-3′-ethyl-5,5′-dimethyloxacarbocyanine (CYA; ε_M^488 nm 142,000 M^-1cm^-1) at the 5′-end as a common energy donor, and fluorescein or rhodamine derivatives (FAM, R6G, TAMRA, and ROX), attached to a modified thymidine 10 bases away within the primer sequence, as acceptors. With 488-nm excitation, the fluorescence emission intensity of these 4 ET primers is 1.4-24-fold stronger than that of the corresponding primers labeled only with the single acceptor dye. When compared with the corresponding ET primers with a fluorescein derivative (FAM; ε_M^488 nm 60,000 M^-1 cm^-1) as donor, the fluorescence emissions of primers with CYA as donor and FAM, R6G, TAMRA, and ROX as acceptors are 0.8-, 1.0-, 1.7-, and 1.7-fold, resp., as intense. The low fluorescence quantum yield of the CYA donor resulted in distinct fluorescence signals for the DNA-sequencing fragments with much lower crosstalk between the 4 detection channels than that seen with ET primers based on a FAM donor. With single-stranded M13mp18 DNA as the template, the CYA ET primers provided DNA sequences on a 4-color capillary sequencer with 100% accuracy in the first 500 bases. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Gold(III) complexes with imidazole, benzoxazole, purine and pyrimidine derivatives was written by Radanovic, Dusan J.;Matovic, Zoran D.;Ponticelli, Gustavo;Scano, Paola;Efimenko, Inessa A.. And the article was included in Transition Metal Chemistry (Dordrecht, Netherlands) in 1994.SDS of cas: 5676-58-4 This article mentions the following:

The synthesis and characterization of Au^III complexes with several heterocyclic ligands are reported. The compounds are [AuX₃(L)], where L = N-methylimidazole (N-MeIz), N-ethylimidazole (N-EtIz), N-propylimidazole (N-PrIz), benzoxazole (BO), 2-methylbenzoxazole (2-MeBO), 2,5-dimethylbenzoxazole (2,5-diMeBO), 2-aminopyrimidine (2-APm), 4(6)-hydroxypyrimidine [4(6)-hydrPm] or hypoxanthine (Hypox) and X = Cl or Br. Elemental anal., conductivity measurements and spectral studies were used for the characterization of the complexes. A square-planar geometry with N-bonded heterocyclic ligands is suggested. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4SDS of cas: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.SDS of cas: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

A Mild, Efficient and Reusable Solid Phosphotungstic Acid Catalyst Mediated Synthesis of Benzoxazole Derivatives: A Grinding Approach was written by Patil, Mahadeo R.;Yelamaggad, Aditya;Keri, Rangappa S.. And the article was included in Letters in Organic Chemistry in 2016.Application of 99586-31-9 This article mentions the following:

Herein, PTA catalyzed synthesis of 2-arylbenzoxazoles from 2-aminophenols and different aromatic aldehydes using a grinding strategy in excellent yield is reported. The use of this reusable catalyst under solvent-free conditions has made this protocol practical, environmentally friendly and economically attractive. The simple work-up procedure, the short reaction times, the mild reaction conditions, the high yields of products and the non-toxicity of the catalyst are other advantages of the present method. This protocol approaches combines the advantages of both focused library synthesis and diversity oriented synthesis because of the simplification of reaction protocol. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Application of 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Although benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Application of 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Synthesis of N-octadecylsquarylium dye was written by Tanaka, Motoo;Sekiguchi, Tatsuo;Kawabata, Yasujiro;Nakamura, Takayoshi;Manda, Eiichiro. And the article was included in Nippon Kagaku Kaishi in 1987.Recommanded Product: 5676-58-4 This article mentions the following:

The synthesis of N-octadecylsquarylium dyes I (R = H, Me, OMe, Cl; X = CMe₂, S, Se) and II (R¹ = Me, Et; R₂ = H, Me, OH) was studied. A mixture of 2 mol N-octadecylated intermediate and 1 mol squaric acid was refluxed 24 h in 2:3 (volume) PhCl-1-pentanol (Method A), or heated 5 h at 160° in the presence of Nafion H resin (Method B). Method B gave better yields than method A. The yields of I were affected by the electronegativity of X and were in the order CMe₂ > Se > S > O. In the case of II good yields were attained for R² which was an electron-releasing substituent such as OH or Me. IR and NMR measurements revealed that I and II had sym. 1,3-bonded squarylium rings, consistent with the results of N-Me squarylium dyes reported by A. Treibs and K. Jacob (1966,1698). In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Recommanded Product: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Mesoporous Poly(melamine-formaldehyde): A Green and Recyclable Heterogeneous Organocatalyst for the Synthesis of Benzoxazoles and Benzothiazoles Using Dioxygen as Oxidant was written by Yang, Daoshan;Liu, Peng;Zhang, Ning;Wei, Wei;Yue, Mingbo;You, Jinmao;Wang, Hua. And the article was included in ChemCatChem in 2014.SDS of cas: 99586-31-9 This article mentions the following:

A simple, highly efficient, and sustainable strategy for the synthesis of benzoxazole and benzothiazole derivatives was developed by using inexpensive, green, readily available, and recyclable mesoporous poly(melamine-formaldehyde) as a green, heterogeneous organocatalyst. The corresponding substituted benzoxazoles and benzothiazoles were obtained in good to excellent yields by aerobic oxidation of o-substituted aminobenzenes with various aldehydes under dioxygen atm. The catalyst can be completely recovered through simple filtration to be reused more than six times without significant loss of catalytic activity. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9SDS of cas: 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.SDS of cas: 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Copper-Catalyzed Direct C-H Bond Arylation of Benzoxazoles with Anilines was written by Feng, Pengju;Ma, Guojian;Zhang, Tianyu;Wang, Changwei. And the article was included in Asian Journal of Organic Chemistry in 2018.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

An efficient and easily managed protocol was developed for the synthesis of 2-aryl-benzoxazoles/benzothiazoles I [R = H, 5-Me, 5-Cl, 5-Br, 5-CO₂Et; R¹ = 2-Me, 4-Cl, 3-Br, etc.; X = O, S; Y = CH, N] by using a copper-catalyzed C-H arylation reaction between benzoxazole derivatives and in situ generated aryl diazonium salts. Under the optimized conditions a wide variety of products I were selectively obtained in moderate to good yields. Diphenylamine and 2,3′-bipyridine were also obtained under the same reaction conditions by employing aniline and pyridin-3-amine resp., as the sole starting material. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Electronic and vibrational spectra of 2-chloro-and 2,5-dimethyl benzothiazole and 2,5-dimethyl benzoxazole was written by Agrawal, Saumya;Srivastava, R. L.;Shukla, M. M.. And the article was included in Acta Ciencia Indica, Physics in 1993.Related Products of 5676-58-4 This article mentions the following:

This paper contains the anal. and assignment of electronic absorption spectra of 2-chloro- and 2,5-di-Me benzothiazole and 2,5-di-Me benzoxazole in liquid and vapor state in the region 50000-28000 cm^-1 together with their IR absorption spectra in the region 40000-400 cm^-1. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

DMF-Assisted Radical Cyclization of o-Isocyanodiaryl Ethers via 1,5-Aryl Migration: Construction of 2-Arylbenzoxazoles was written by Yuan, Sitian;Ye, Xiaoling;Cai, Jingyu;Song, Zhibin;Tan, Yuxing;Peng, Yiyuan;Ding, Qiuping. And the article was included in Journal of Organic Chemistry in 2022.Recommanded Product: 99586-31-9 This article mentions the following:

A novel DMF-assisted radical cyclization of o-isocyanodiaryl ethers 2-CN-3-R¹-4-R² -5-R³ C₆HOR (R = 2-tert-butylphenyl, 2-phenylphenyl, pyridin-2-yl; R¹ = H, Me, Cl; R² = H, Me, Cl; R³ = H, Me) via 1,5-aryl migration has been developed for the synthesis of a series of 2-arylbenzoxazoles I and 2-phenyloxazolo[4,5-b]pyridine by the FeCl₃/TBHP/Et₃N catalytic system in DMF. However, N,N-dimethylbenzo[d]thiazole-2-carboxamide and N,N-dimethylbenzo[d]selenazole-2-carboxamide were obtained from the corresponding substrate 2-isocyanophenyl p-methoxyphenyl thioether and 2-isocyanodiphenyl selenoether under the same conditions. A possible mechanism may involve aryl 1,5-migration and DMF-assisted radical cyclization of o-isocyanodiaryl ethers I. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem