Research speed reading in 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, new energy materials, preparation and modification of special coatings. 363-72-4, Name is Pentafluorobenzene, molecular formula is C6HF5, belongs to benzoxazole compound. In a document, author is Singh, Varinder, HPLC of Formula: https://www.ambeed.com/products/363-72-4.html.
A novel series of benzoxazolyl linked benzylidene based rhodanine and their cyclic analogs were synthesized, characterized and evaluated for their alpha-amyloglucosidase inhibitory activity. Out of eight target compounds, two compounds (4b and 5b) displayed potent inhibitory activity against alpha-amyloglucosidase with IC50 values in the range of 0.24 +/- 0.01-0.94 +/- 0.01 A mu M as compared to standard drug acarbose. Among all the tested compounds, compound 5b containing rhodanine at 3-position of phenyl was found to be the most active inhibitor of alpha-amyloglucosidase. Docking studies showed the existence of potential H-bonding interactions between synthesized compounds and alpha-glucosidase which might be responsible for good biological activity.
The π-electrons of these planar compounds are free to cycle around the circular arrangements of atoms found in the aromatic moieties. This stems from the resonance found in planar ring systems, like benzene, and C6HF5. HPLC of Formula: https://www.ambeed.com/products/363-72-4.html.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem