9/28 News An Update On The Compound Challenge: C3H4F4O

Safety of 2,2,3,3-Tetrafluoropropan-1-ol, This is part of our series highlighting examples of​​ C3H4F4O in action by scientists around the world.

The chromogenic properties of 2-(2-carbomethoxy-3,4-dichloro-6-hydroxyphenyl)benzoxazole (1) were studied. Solvatochromism of 1 was observed at keto-enol equilibrium due to the ground state intramolecular proton transfer (GSIPT). It was found that solvents with a good hydrogen bond acceptor (beta) ability were able to stabilise the keto form of 1. The excited-state intra molecular proton transfer (ESIPT) in molecules of 1 resulted in intense fluorescence with an anomalous Stokes shift of up to 8493 cm 1 and quantum yields of 0.08-0.19. The keto-form of 1 exhibits negative T-type photochromism with a thermally reversible photoconversion to the enol form. The complexes of ligand 1 with Zn(II) and Cd(II) were synthesised. According to X-ray structural analysis, the zinc complex is the neutral complex, which is formed by two oxazole-N and two phenol O donors of ligand 1 which crystallise in a centrosymmetric group with the zinc ion located on the inversion centres. The synthesised complexes possess effective blue fluorescence and resistance to photodegradation.

Safety of 2,2,3,3-Tetrafluoropropan-1-ol, This is part of our series highlighting examples of​​ C3H4F4O in action by scientists around the world.

Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem