Synthetic Route of 181040-42-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.181040-42-6, Name is 6-(Bromomethyl)benzo[d]oxazole, molecular formula is C8H6BrNO. In a Article£¬once mentioned of 181040-42-6
Site selective syntheses of [3H]omeprazole using hydrogen isotope exchange chemistry
Omeprazole (Prilosec) is a selective and irreversible proton pump inhibitor used to treat various medical conditions related to the production of excess stomach acids. It functions by suppressing secretion of those acids. Radiolabeled compounds are commonly employed in the drug discovery and development process to support efforts including library screening, target identification, receptor binding, assay development and validation and safety assessment. Herein, we describe synthetic approaches to the controlled and selective labeling of omeprazole with tritium via hydrogen isotope exchange chemistry. The chemistry may also be used to prepare tritium labeled esomeprazole (Nexium), the active pure (S)-enantiomer of omeprazole.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 181040-42-6, and how the biochemistry of the body works.Synthetic Route of 181040-42-6
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem