As a common heterocyclic compound, it belongs to benzoxazole compound, name is Benzo[d]oxazol-2-amine, and cas is 4570-41-6, its synthesis route is as follows.
The Schiff base, N-((thiophen-2-yl)methyleneimino)benzoxazole (Htbi) was isolated as an orange crystalline substance from the equimolar condensation reaction between 2-aminobenzoxazole (0.250 g; 1.86 mmol) and 2-thiophenecarboxaldehyde (0.209; 1.86 mmol). The reaction was conducted in 40 cm3 of dry toluene and in the presence 3 drops of piperidine, under nitrogen for 6 hours followed by reducing the reaction mixture to 5 cm3 and cooling it in an ice-bath to induce crystallization. The reducing agent, sodium borohydride (0.025 g, 0.66 mmol) in ethanol ethanol (10 cm3) was added dropwise to a stirring solution of ethanol (20 cm3) containing 0.15 g of Htbi (0.66 mmol) at room temperature. The reaction mixture was then refluxed for an hour and thereafter cooled to room temperature by adding an equal volume of cold distilled water. A white precipitate instantaneously formed which was collected, washed with distilled water and dried under vacuum. Yield = 88percent,
4570-41-6, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,4570-41-6 ,Benzo[d]oxazol-2-amine, other downstream synthetic routes, hurry up and to see
Reference£º
Article; Booysen, Irvin Noel; Adebisi, Abimbola; Akerman, Matthew Piers; Inorganica Chimica Acta; vol. 433; (2015); p. 13 – 20;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem