As a common heterocyclic compound, it belongs to benzoxazole compound, name is 2-Benzoxazolinone, and cas is 59-49-4, its synthesis route is as follows.
To benzoxalinone (1.35 g, 1.00 mmol) in water (20 mL) was added NaOH (0.500 g, 1.25 mmol)and the mixture was stirred at room temperature until it became homogeneous. Dimethyl sulfate (1.51 g,1.20 mmol) was added dropwise to the mixture, and the reaction mixture was stirred rapidly at roomtemperature until precipitation was observed. Then, the reaction mixture was stirred for additional 2 h.The reaction mixture was neutralized with 1 M HCl, and the precipitate was collected by filtration anddried over P2O5 under vacuum to afford 2 as a light brown solid (1.162 g, 78%): 1H NMR (300 MHz,CDCl3) delta 7.34 – 7.07 (m, 3H), 6.99 (d, J = 7.3 Hz, 1H), 3.43 (s, 3H). The data were consistent withliterature values.
59-49-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,59-49-4 ,2-Benzoxazolinone, other downstream synthetic routes, hurry up and to see
Reference£º
Article; Zhou, Yuchen; McGillick, Brian E.; Teng, Yu-Han Gary; Haranahalli, Krupanandan; Ojima, Iwao; Swaminathan, Subramanyam; Rizzo, Robert C.; Bioorganic and Medicinal Chemistry; vol. 24; 20; (2016); p. 4875 – 4889;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem