Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 540-36-3, Name is 1,4-Difluorobenzene. In a document, author is Sansalone, Lorenzo, introducing its new discovery. HPLC of Formula: C6H4F2.
High-Throughput Single-Molecule Spectroscopy Resolves the Conformational Isomers of BODIPY Chromophores
A borondipyrromethene (BODIPY) chromophore is connected to a benzoxazole, benzothiazole, or nitrobenzothiazole heterocycle through an olefinic bridge with trans configuration. Rotation about the two [C-C] bonds flanking the olefinic bridge occurs with fast kinetics in solution, leading to the equilibration of four conformational isomers for each compound. Ensemble spectroscopic measurements in solutions fail to distinguish the coexisting isomers. They reveal instead averaged absorption and emission bands with dependence of the latter on the excitation wavelength. Using high-throughput single-molecule spectroscopy, two main populations of single molecules with distinct spectral centroids are observed for each compound on glass substrates. Computational analyses suggest the two populations of molecules to be conformational isomers with antiperiplanar and periplanar arrangements of the BODIPY chromophores about its [C-C] bond to the olefinic bridge. Thus, statistical analysis of multiple single-molecule emission spectra can discriminate stereoisomers that would otherwise be impossible to distinguish by ensemble measurements alone.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 540-36-3 help many people in the next few years. HPLC of Formula: C6H4F2.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem