Chemistry, like all the natural sciences, Formula: CH2F3NO2S, begins with the direct observation of nature¡ª in this case, of matter.421-85-2, Name is Trifluoromethanesulfonamide, SMILES is O=S(C(F)(F)F)(N)=O, belongs to benzoxazole compound. In a document, author is Zhong, Xiuli, introduce the new discover.
A mitochondria-targeted fluorescent probe based on coumarin-pyridine derivatives for hypochlorite imaging in living cells and zebrafish
Hypochlorite plays a critical role in various physiological processes and is involved in many diseases. Thus, real-time, rapid, and accurate monitoring of hypochlorite has important medical and physiological significance. Herein, a novel coumarin-pyridine derivative (CPD) probe was designed and synthesized, which exhibited fantastic advantages, such as a rapid response (within 10 s), naked eye recognition, large Stokes shift (185 nm), dual-channel detection, and high selectivity and sensitivity toward OCl- (detection limit 0.012 mu M, S/N = 3). Furthermore, the current CPD probe was successfully used to image OCl- in the mitochondria of both A549 cells and zebrafish, which further demonstrated its suitability for practical applications in biological systems.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 421-85-2. Formula: CH2F3NO2S.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem