Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 348-54-9, Name is 2-Fluoroaniline, SMILES is NC1=CC=CC=C1F, belongs to benzoxazole compound. In a document, author is Ramakrishna, Kankanala, introduce the new discover, Product Details of 348-54-9.
Coordination Assisted Distal C-H Alkylation of Fused Heterocycles
Distal C-H bond functionalization of heterocycles remained extremely challenging with covalently attached directing groups (DG). Lack of proper site for DG attachment and inherent catalyst poisoning by heterocycles demand alternate routes for site selective functionalization of their distal C-H bonds. Utilizing non-productive coordinating property to hold the heterocycle into the cavity of a template system in a host-guest manner, we report distal C-H alkylation (C-5 of quinoline and thiazole, C-7 of benzothiazole and benzoxazole) of heterocycles. Upon complexation with heterocyclic substrate, nitrile DG in template directs the metal catalyst towards close vicinity of the specific distal C-H bond of the heterocycles. Our hypothesized pathway has been supported by various X-ray crystallographically characterized intermediates.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 348-54-9 is helpful to your research. Product Details of 348-54-9.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem