Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 372-38-3, Name is 1,3,5-Trifluorobenzene. In a document, author is Wang, Wei, introducing its new discovery. Computed Properties of C6H3F3.
Construction of S-CF2/O-CF2 bonds via inter intramolecular radical nucleophilic substitution reaction
A facile and efficient method for construction of S-CF2 or O-CF2 bonds through intermolecular radical nucleophilic substitution (S(RN)1) reaction of 2-bromo-2,2-difluoro-N-phenylacetamide and thiophenols or phenols was developed, which has also been successfully utilized in the intramolecular S(RN)1 reaction to generate a new O-CF2 bonds for synthesis of biologically important 2,2-difluoro-2H-benzo [1,4]oxazin-3-one. The protocol enables an efficient access to gem-difluoromethylene-containing thioethers or ethers and oxazin heterocycles with good to excellent yields by inter/intramolecular radical nucleophilic substitution reaction under mild reaction conditions. (C) 2020 Elsevier Ltd. All rights reserved.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 372-38-3 help many people in the next few years. Computed Properties of C6H3F3.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem