2343-89-7, Name is Methyl 2-fluoroacrylate, molecular formula is C4H5FO2, belongs to benzoxazole compound, is a common compound. In a patnet, author is Molavipordanjani, Sajjad, once mentioned the new application about 2343-89-7, HPLC of Formula: C4H5FO2.
Tc-99m-labeled Small Molecules for Diagnosis of Alzheimer’s Disease: Past, Recent and Future Perspectives
Background: Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disease. Its prominent hallmarks are extracellular deposition of beta-amyloids (amyloid plaques), intracellular neurofibrillary tangles (NTFs), neurodegeneration and finally loss of cognitive function. Hence, AD diagnosis in the early stage and monitoring of the disease are of great importance. Methods: In this review article, we have reviewed recent efforts for design, synthesis and evaluation of Tc-99m labeled small molecule for AD imaging purposes. Results: These small molecules include derivatives of Congo red, benzothiazole, benzofuran, benzoxazole, naphthalene, biphenyl, chalcone, flavone, aurone, stilbene, curcumin, dibenzylideneacetone, quinoxaline, etc. The different aspects of Tc-99m-labeled small molecules including chemical structure, their affinity toward amyloid plaques, BBB permeation and in vivo/vitro stability will be discussed. Conclusion: The fmdings of this review confirm the importance of Tc-99m-labeled small molecules for AD imaging. Future studies based on the pharmacophore of these designed compounds are needed for improvement of these molecules for clinical application.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 2343-89-7. The above is the message from the blog manager. HPLC of Formula: C4H5FO2.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem