Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 348-54-9, Name is 2-Fluoroaniline, SMILES is NC1=CC=CC=C1F, belongs to benzoxazole compound. In a document, author is Murata, Yuki, introduce the new discover, Application In Synthesis of 2-Fluoroaniline.
One-pot reaction for the synthesis of N-substituted 2-aminobenzoxazoles using triphenylbismuth dichloride as cyclodesulfurization reagent
The treatment of various 2-aminophenols with isothiocyanates afforded thioureas, which were reacted in situ with triphenylbismuth dichloride in the presence of triethylamine to give the expected N-substituted benzoxazol-2-amines in good to excellent yields. Triphenylbismuth dichloride promoted the successful cyclodesulfurization of thioureas with short reaction times under mild reaction conditions. This reaction is the first example of the synthesis of heterocyclic rings using a pentavalent organobismuth reagent. (C) 2018 Elsevier B.V. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 348-54-9 is helpful to your research. Application In Synthesis of 2-Fluoroaniline.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem