Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Wu, Dan, once mentioned the application of 348-54-9, Name is 2-Fluoroaniline, molecular formula is C6H6FN, molecular weight is 111.1169, MDL number is MFCD00007642, category is benzoxazole. Now introduce a scientific discovery about this category, Quality Control of 2-Fluoroaniline.
Synthesis of Fully Substituted Oxazoles via an NFSI/KF-Mediated Double Bond Cleavage-Rearrangement Cascade
An NFSI/KF-mediated scission/recombination of C-C double bonds for [4+1] annulation is reported, leading to the efficient synthesis of a wide range of fully substituted oxazoles in good to excellent yields under mild redox-neutral conditions. This methodology might open a new entry for the preparation of structurally applicable heterocyclic systems in a highly functional-group-compatible manner.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem