The important role of 59-49-4

59-49-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,59-49-4 ,2-Benzoxazolinone, other downstream synthetic routes, hurry up and to see

Name is 2-Benzoxazolinone, as a common heterocyclic compound, it belongs to benzoxazole compound, and cas is 59-49-4, its synthesis route is as follows.

Ar gas protection, Ice bath conditions, NaH (910 mg, 47.9 mmol) was added to dry THF and benzoxetine was added (3.6 g, 26.6 mmol) Dissolved in anhydrous THF, Methyl iodide (5.7 g, 40 mmol) was slowly added, Reaction to ice bath to room temperature overnight reaction. After the reaction was stopped, the mixture was concentrated, diluted with water, extracted with DCM, dried and separated on a light reddish brown solid (2.8 g, 71%)

59-49-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,59-49-4 ,2-Benzoxazolinone, other downstream synthetic routes, hurry up and to see

Reference:
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Xu Boling; Shen Zhufang; Bie Jianbo; Mu Yongzhao; Chen Hualong; Liu Lvnan; Zhou Jie; Li Caina; Cao Ran; Huan Yi; Sun Shujuan; (258 pag.)CN107098846; (2017); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem