It is a common heterocyclic compound, the benzoxazole compound, 5-Chlorobenzo[d]oxazole-2(3H)-thione, cas is 22876-19-3 its synthesis route is as follows.
(1) Synthesis of 4beta-S-(6-chlorobenzoxazole-2)-4′-demethylepipodophyllotoxin: 400 mg (1 mmol)4′-desmethylepipodophyllotoxin, 1472 mg (8 mmol) of 6-chlorobenzoxazole-2-thiol, dried under vacuum for 1 h at -10 C15 mL of trifluoroacetic acid was used as a solvent, and the mixture was stirred at atmospheric pressure for 1 to 3 hours, and chloroform acetone was used as a developing agent to detect the reaction end point. Add the reaction systemThe mixture is poured into 20 to 50 volumes of deionized water, and the filter cake is collected by filtration, and washed to obtain a crude product.
22876-19-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,22876-19-3 ,5-Chlorobenzo[d]oxazole-2(3H)-thione, other downstream synthetic routes, hurry up and to see
Reference：
Patent; Tang Yajie; Zhao Wei; (23 pag.)CN108285456; (2018); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem