Research speed reading in 2021. Catalysts allow a reaction to proceed that has a lower activation energy than the uncatalyzed reaction. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. 51-67-2, Name is Tyramine, molecular formula is , belongs to benzoxazole compound. In a document, author is Oshimoto, Kohei, Quality Control of Tyramine.
We describe herein the synthetic method to benzoxazole derivatives via the copper-catalyzed hydroamination of alkynones with 2-aminophenols. The method produced a wide variety of functionalized benzoxazole derivatives in good yields. Preliminary mechanistic experiments revealed that the reaction would proceed through the copper-catalyzed hydroamination of alkynones and the sequential intramolecular cyclization of beta-iminoketones/elimination of acetophenone promoted by the copper catalyst.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem