New discoveries in chemical research and development in 2021. As an important bridge between the micro, chemistry is one of the main methods and means for humans to understand and transform the material world. In an article, author is Wu, Yu-Ran, once mentioned the application of 1714-29-0, Name: 1-Bromopyrene, category is benzoxazole. Now introduce a scientific discovery about this category.
Eight glycosyl benzoxazole derivatives are synthesized by nucleophilic addition reactions of glycosyl isothiocyanate witho-aminophenol in tetrahydrofuran. The reaction conditions are optimized, and good yields (86%-94%) were obtained. The structures of all new products are confirmed by infrared,H-1 nuclear magnetic resonance, and high-resolution mass spectrometry (electrospray ionization). In addition, the in vitro cholinesterase inhibitory activities of these new compounds are tested by Ellman’s method.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem