Analyzing the synthesis route of 59-49-4

With the synthetic route has been constantly updated, we look forward to future research findings about 2-Benzoxazolinone,belong benzoxazole compound

As a common heterocyclic compound, it belong benzoxazole compound,2-Benzoxazolinone,59-49-4,Molecular formula: C7H5NO2,mainly used in chemical industry, its synthesis route is as follows.,59-49-4

General procedure: Nitric acid (68%, 5.30 cm3, 80 mmol) cooled to 0-5Cwas added dropwise to a solution of benzoxazolinone (10 mmol) in 20 cm3 of acetic anhydride. The mixture was stirred at 0-5C for 3 h. The precipitate was filtered, washed with cold H2O, dried, and recrystallized from suitable solvent to afford the corresponding nitrobenzoxazolones compounds 3a (67.77%) and 3b (91%).

With the synthetic route has been constantly updated, we look forward to future research findings about 2-Benzoxazolinone,belong benzoxazole compound

Reference£º
Article; Yahia, Wassila; Nacereddine, Abdelmalek Khorief; Seddiki, Khemissi; Liacha, Messaoud; Nippert; Revue Roumaine de Chimie; vol. 60; 9; (2015); p. 853 – 859;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem