New research progress on 2892-51-5 in 2021.Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. 2892-51-5, Name is 3,4-Dihydroxy-3-cyclobutene-1,2-dione, molecular formula is , belongs to benzoxazole compound. In a document, author is Wang, Kezhou, Application In Synthesis of 3,4-Dihydroxy-3-cyclobutene-1,2-dione.
A series of 2-(cyanomethyl)azaarenes containing benzothiazole or benzoxazole were designed and synthesized for asymmetric alpha-functionalization with N-Boc-amino sulfones. The Mannich adducts were obtained in high yields with good diastereo- and enantioselectivities. Aryl substituted amino sulfones were tolerated under the current conditions, and the reaction can be performed on gram scale in good results.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem