I found the field of Science & Technology – Other Topics very interesting. Saw the article The [3+2] Annulation of CF3-Ketimines by Re Catalysis: Access to CF3-Containing Amino Heterocycles and Polyamides published in 2020. Category: benzoxazole, Reprint Addresses Xiong, HY; Zhang, GW (corresponding author), Henan Univ, Coll Chem & Chem Engn, Inst Organ Funct Mol, Kaifeng 475004, Peoples R China.. The CAS is 92-86-4. Through research, I have a further understanding and discovery of 4,4′-Dibromobiphenyl
Transition metal catalyzed [3 + 2] annulation of imines with double bonds via directed C-H activation offers a direct access to amino cyclic motifs. However, owing to weak coordination and steric hindrance, trifluoromethylated ketimines have been an unaddressed challenge for TM-catalyzed annulations. Here, a rhenium-catalyzed [3 + 2] annulation of trifluoromethylated ketimines with isocyanates via C(sp(2))-H activation has been disclosed. This approach provides an efficient platform for rapid access to a privileged library of CF3-containing iminoisoindolinones and polyamides by utilizing challenging CF3-ketimines as the annulation component. The capability of gram scale synthesis, the post-functionalization of the cyclization adduct, the derivation of complex natural molecules and the facile synthesis of polyamides highlight a diversity of synthetic potential of the current methodology.
About 4,4′-Dibromobiphenyl, If you have any questions, you can contact Zhang, SS; Liu, XY; Chang, ZB; Qiao, XX; Xiong, HY; Zhang, GW or concate me.. Application In Synthesis of 4,4′-Dibromobiphenyl
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem