4570-41-6, Benzo[d]oxazol-2-amine is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a suspension of benzo[d]oxazol-2-amine (5.Og, 37.3mmol) in DMF (5OmL) was added 20.0 M NaOH (1.86mL, 37.3mmol) at 0 00. The reaction mixture was stirred for 10 mm and CS2 (6.32mL, 93.2mmol) was added dropwise at 0 00 and the reaction mixture was further stirred for 10 mm at 0 00 An additional portion of 20.0 M NaOH (1.86mL, 37.3mmol) was added at 0 00 and reaction mixture was again stirred for 10 mm at 0 00 Finally, CH3I (5.84mL, 93.2mmol) was added dropwise at 0 00. The reaction mixture was stirred at rt for 30 mm. The TLC showed reaction to be complete. The mixture was poured into ice-water (lOOmL) and the precipitated solid was filtered , washed with water(5OmL) followed by hexane (3OmL) and dried under reduced pressure to obtain dimethyl benzo[d]oxazol-2- ylcarbonimidodithioate as an off white solid . Yield: 6.92g (78percent). MS (ESl+) for CHNOS m/z 239.03 [M+H] 1H NMR (400 MHz, DMSO-d6): 7.64 (bs, 2H), 7.32 (bs, 2H), 2.67 (bs, 6H).
4570-41-6, 4570-41-6 Benzo[d]oxazol-2-amine 20707, abenzoxazole compound, is more and more widely used in various fields.
Reference£º
Patent; DISCUVA LTD.; MEO, Dr Paul; KHAN, Dr. Nawaz; (284 pag.)WO2018/37223; (2018); A1;,
Benzoxazole – Wikipedia
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