SDS of cas: 92-86-4. Recently I am researching about (Q)SAR APPLICATION TOOLBOX; ACUTE TOXICITY; STRUCTURAL ALERTS; CLASSIFICATION; MUTAGENICITY; TOXTREE; PREDICTION; CHEMICALS; PRODUCTS, Saw an article supported by the National Research Council of Science & Technology (NST) grant by the South Korean government (MSIP) [CAP-17-01-KIST Europe]; [11911]. Published in JOURNAL OF VISUALIZED EXPERIMENTS in CAMBRIDGE ,Authors: Bohlen, ML; Jeon, HP; Kim, YJ; Sung, B. The CAS is 92-86-4. Through research, I have a further understanding and discovery of 4,4′-Dibromobiphenyl
Computational analyses of toxicological processes enables high-throughput screening of chemical substances and prediction of their endpoints in biological systems. In particular, quantitative structure-activity relationship (QSAR) models have been increasingly applied to assess the environmental effects of a plethora of toxic materials. In recent years, some more highlighted types of toxicants are endocrine disruptors (EDs, which are chemicals that can interfere with any hormone-related metabolism). Because EDs may significantly affect animal development and reproduction, rapidly predicting the adverse effects of EDs using in silico techniques is required. This study presents an in silico method to generate prediction data on the effects of representative EDs in aquatic vertebrates, particularly fish species. The protocol describes an example utilizing the automated workflow of the QSAR Toolbox software developed by the Organization for Economic Co-operation and Development (OECD) to enable acute ecotoxicity predictions of EDs. As a result, the following are determined: (1) calculation of the numerical correlations between the concentration for 50% of lethality (LC50) and octanol-water partition coefficient (K-ow), (2) output performances in which the LC50 values determined in experiments are compared to those generated by computations, and (3) the dependence of estrogen receptor binding affinity on the relationship between K-ow and LC50.
SDS of cas: 92-86-4. Bye, fridends, I hope you can learn more about C12H8Br2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem