With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.59-49-4,2-Benzoxazolinone,as a common compound, the synthetic route is as follows.
General procedure: Nitric acid (68%, 5.30 cm3, 80 mmol) cooled to 0-5Cwas added dropwise to a solution of benzoxazolinone (10 mmol) in 20 cm3 of acetic anhydride. The mixture was stirred at 0-5C for 3 h. The precipitate was filtered, washed with cold H2O, dried, and recrystallized from suitable solvent to afford the corresponding nitrobenzoxazolones compounds 3a (67.77%) and 3b (91%)., 59-49-4
59-49-4 2-Benzoxazolinone 6043, abenzoxazole compound, is more and more widely used in various fields.
Reference£º
Article; Yahia, Wassila; Nacereddine, Abdelmalek Khorief; Seddiki, Khemissi; Liacha, Messaoud; Nippert; Revue Roumaine de Chimie; vol. 60; 9; (2015); p. 853 – 859;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem