Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 503538-69-0, is researched, Molecular C38H24F4O4P2, about Asymmetric Hydrogenation of Cyclic Imines and Enamines: Access to 1,5-Benzodiazepine Pharmacophores, the main research direction is asym hydrogenation benzodiazepinone rhodium difluoroPhos catalyst.Application of 503538-69-0.
A new strategy towards the pharmacol. relevant class of dihydro-1,5-benzodiazepines was developed by applying a rhodium-catalyzed asym. hydrogenation. The approach represents an efficient protocol providing access to the optically active products I (R1 = Ph, 4-MeC2H4, 2-furyl, Me, etc., R2 = H, 7-Me) in excellent yields (up to 99%) and with high enantioselectivities (up to 92% ee). The versatility of the methodol. was demonstrated by a broad substrate scope including alkyl, aryl, and heteroaryl substituents as well as halides. Furthermore, investigations regarding the reaction mechanism were performed and unraveled a preferred reaction of the tautomeric enamine in the rhodium-catalyzed asym. hydrogenation.
When you point to this article, it is believed that you are also very interested in this compound(503538-69-0)Application of 503538-69-0 and due to space limitations, I can only present the most important information.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem