The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole(SMILESS: FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1,cas:503538-69-0) is researched.Electric Literature of C13H19ClN2O. The article 《Palladium/Zinc Co-Catalyzed syn-Stereoselectively Asymmetric Ring-Opening Reaction of Oxabenzonorbornadienes with Phenols》 in relation to this compound, is published in Chemistry – A European Journal. Let’s take a look at the latest research on this compound (cas:503538-69-0).
A new palladium/zinc co-catalyst system associated with chiral (R)-Difluorphos for asym. ring-opening reaction of oxabenzonorbornadienes with phenols is reported. This catalyst system allows the formation of cis-2-aryloxy-1,2-dihydronaphthalen-1-ol I (Ar = Ph, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, etc.) and II (R = 5,8-(OCH3)2, 5,8-(CH3)2, 6,7-Br2, 6,7-OCH2O, 6,7-(OCH3)2) products in good yields (up to 95 % yield) with excellent enantioselectivities (up to 99 % ee). The cis-configuration of the product has been confirmed by X-ray crystal structure anal. To the best of our knowledge, it represents the first example in ring-opening reactions of bicycloalkenes with heteronucleophiles in a syn-stereoselective manner.
Compound(503538-69-0)COA of Formula: C38H24F4O4P2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole), if you are interested, you can check out my other related articles.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem