The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors, the main research direction is mercaptobenzimidazole benzyl alc etherification; benzimidazole thioether preparation cyclooxygenase inhibitor; mercaptobenzothiazole benzyl alc etherification; benzothiazole thioether preparation cyclooxygenase inhibitor; mercaptobenzoxazole benzyl alc etherification; benzoxazole thioether preparation cyclooxygenase inhibitor.SDS of cas: 27231-36-3.
A series of 2-[[(2-alkoxy-6-pentadecylphenyl)methyl]thio]-1H-benzimidazoles, benzothiazoles and benzoxazoles have been prepared from anacardic acid and their ability to inhibit human cyclooxygenase-2 enzyme (COX-2) investigated. The active compounds were screened for cyclooxygenase-1 (COX-1) inhibition. I (X = NH; R1 = H; R2 = OMe) is 384-fold and I (X = S; R1 = Me; R2 = H) is more than 470-fold selective towards COX-2 compared to COX-1. Thus, this class of compounds may serve as excellent candidates for selective COX-2 inhibition.
In addition to the literature in the link below, there is a lot of literature about this compound(2-Mercapto-5-methylbenzimidazole)SDS of cas: 27231-36-3, illustrating the importance and wide applicability of this compound(27231-36-3).
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem