Wan, Jin-Lin; Huang, Jing-Mei published the artcile< Bromide-Catalyzed Electrochemical Csp3-H Oxidation of Acetonitrile: Stereoselective Synthesis of Heteroaryl Vinyl Sulfides>, Computed Properties of 13451-78-0, the main research area is heteroaryl vinyl sulfide preparation electrochem diastereoselective; acetonitrile heteroaryl thiol oxidative cross coupling reaction bromide catalyst.
An electrochem. oxidative C-H/S-H cross-coupling reaction between acetonitrile and heteroaryl thiols e.g., 1,3-benzoxazole-2-thiol has been developed. Me4NBr is employed as a redox catalyst to oxidize both the Csp3-H of acetonitrile and S-H of heteroaryl thiols. Heteroaryl vinyl sulfides e.g., I were afforded under metal-free and oxidant-free reaction conditions in good yields and stereoselectivities with excellent functional group tolerance. The synthetic applicability of the electrochem. method was further highlighted by its easy scalability.
Advanced Synthesis & Catalysis published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 13451-78-0 belongs to class benzoxazole, and the molecular formula is C7H4FNOS, Computed Properties of 13451-78-0.
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem