With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.17200-30-5,6-Nitrobenzo[d]oxazole,as a common compound, the synthetic route is as follows.
[0004031 To a stirred solution of compound 1 (0.6 g, 1 eq) in methanol (10 mL), Raney nickel (0.1 g) was added. The reaction mixture was stirred at room temperature under hydrogen atmosphere (balloon pressure) for 3 h. The progress of the reaction was monitored by TLC. After completion of the reaction, the reaction mixture was filtered through celite and evaporated under reduced pressure to afford the title compound 6. LCMS (mlz): 135.00 (M + 1).
17200-30-5, The synthetic route of 17200-30-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; BIOMARIN PHARMACEUTICAL INC.; BHAGWAT, Shripad; WANG, Bing; LUEDTKE, Gregory R.; SPYVEE, Mark; (490 pag.)WO2016/57834; (2016); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem