Application of nano SnO2 as a green and recyclable catalyst for the synthesis of 2-aryl or alkylbenzoxazole derivatives under ambient temperature was written by Vahdat, Seyed Mohammad;Raz, Shima Ghafouri;Baghery, Saeed. And the article was included in Journal of Chemical Sciences (Bangalore, India) in 2014.Synthetic Route of C9H9NO This article mentions the following:
Application of nano-SnO2 as an efficient and environmentally benign catalyst was explored for the synthesis of 2-arylbenzoxalzole derivatives I [R = Ph, 2-HOC6H4, 2-MeOC6H4, 2-furyl, 3-Cl, 2-thienyl, etc., R1 = H, Me, Cl, NO2] or 2-alkylbenzoxazole derivatives I [R = H, Me, Et, R1 = H, Me, Cl] via condensation reaction of 2-aminophenols with aryl aldehydes or orthoesters, resp. The SnO2 nanocatalyst is reusable, cheap and eco-friendly. This catalyst offers several advantages including mild reaction conditions, high yield of products, lower catalyst loading and shorter reaction times with simple exptl. and isolation procedures. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Synthetic Route of C9H9NO).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Synthetic Route of C9H9NO
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem