Copper-catalyzed direct thiolation of azoles with aliphatic thiols was written by Zhou, An-Xi;Liu, Xue-Yuan;Yang, Ke;Zhao, Shu-Chun;Liang, Yong-Min. And the article was included in Organic & Biomolecular Chemistry in 2011.Reference of 132227-03-3 This article mentions the following:
Cu(ii)-catalyzed direct thiolation of azoles with thiols is described via intermol. C-S bond formation/C-H functionalization under oxidative conditions. Both aryl thiols and aliphatic thiols are used as coupling partners, and furnished the thiolation products in moderate to good yields. The reaction is compatible with a wide range of heterocycles including oxazole, thiazole, imidazole and oxadiazole. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Reference of 132227-03-3).
5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Reference of 132227-03-3
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem