4570-41-6, Name is Benzo[d]oxazol-2-amine, belongs to benzoxazole compound, is a common compound. 4570-41-6In an article, authors is Anand, Namrata, once mentioned the new application about 4570-41-6.
Identification of 1-[4-benzyloxyphenyl)-but-3-enyl]-1H-azoles as new class of antitubercular and antimicrobial agents
A series of 1-[(4-benzyloxyphenyl)-but-3-enyl]-1H-azoles has been identified as potent antitubercular agents against Mycobacterium tuberculosis. Synthesis of compounds involved acid catalyzed ring-opening of cyclopropyl ring of phenyl cyclopropyl methanols followed by nucleophilic attack of the azoles on the carbocation intermediates. Several of the compounds 26, 34, and 36 exhibited significant antitubercular activities with MIC value as low as 1.56, 1.56, and 0.61 mug/mL, respectively, comparable to many standard drugs. These compounds were also screened against other strains of bacteria and fungi, and few of them showed good antifungal activity against A. fumigatus, responsible for lung infection.
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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem