Analyzing the synthesis route of 27383-86-4

With the synthetic route has been constantly updated, we look forward to future research findings about Methyl benzo[d]oxazole-2-carboxylate,belong benzoxazole compound

As a common heterocyclic compound, it belong benzoxazole compound,Methyl benzo[d]oxazole-2-carboxylate,27383-86-4,Molecular formula: C9H7NO3,mainly used in chemical industry, its synthesis route is as follows.,27383-86-4

Benzoxazole-2-carboxylic acid hydrazide (4): To a mixture of 3 (0.01 mol) in 10 mL of absolute ethanol and hydrazine hydrate (0.04 mol) was added. Then the reaction mixture was refluxed for 8 h. After completion of the reaction (monitored by TLC), it was then diluted with ice-cold water (20 mL) and the solid obtained was purified by crystallization from ethanol to afford pure product benzoxazole-2-carboxylic acid hydrazide 4. Benzoxazole-2-carboxylic acid N’-acetyl hydrazide (5a-d): To a solution of 4 (0.01 mol) in dioxane (10 mL) corresponding benzoyl chloride (0.01 mol) was added.

With the synthetic route has been constantly updated, we look forward to future research findings about Methyl benzo[d]oxazole-2-carboxylate,belong benzoxazole compound

Reference£º
Article; Vodela, Sunil; Mekala, Raghu Vardhan Reddy; Danda, Ravinder Reddy; Kodhati, Venkateshwarlu; Chinese Chemical Letters; vol. 24; 7; (2013); p. 625 – 628;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem