Analyzing the synthesis route of 72752-81-9

With the synthetic route has been constantly updated, we look forward to future research findings about Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate,belong benzoxazole compound

As a common heterocyclic compound, it belong benzoxazole compound,Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate,72752-81-9,Molecular formula: C9H7NO3S,mainly used in chemical industry, its synthesis route is as follows.,72752-81-9

To a suspension of compound 5.3 (320 g, 1.53 mol) and K2CO3 (276 g, 2 mol) in EtOAC (3 L) was added MeI (238.9 g, 1.68 mol) below 20 C. The mixture was stirred at room temperature for 12 hours. TLC (EtOAc/petroleum ether=1:3) indicated the reaction was complete. Water (2 L) was added to the mixture. The organic phase was separated, dried over Na2SO4 and concentrated to give 5.4 (320 g, 93.8%) as a pink solid.

With the synthetic route has been constantly updated, we look forward to future research findings about Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate,belong benzoxazole compound

Reference£º
Patent; TIBOTEC BVBA; US2010/305073; (2010); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem