90322-32-0, 2-Methylbenzo[d]oxazole-5-carboxylic acid is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,90322-32-0
Following general procedure B, Compound (i?-32 was prepared from compound B-129 (69 mg, 0.39 mmol) and compound (i?)-A-104 (50 mg, 0.32 mmol), with a reaction time of 12 hours. The product was purified by prep-HPLC [Instrument: GX-C; Column: Phenomenex Gemini CI 8 150×30 mm, particle size: 5 mupiiota; Mobile phase: 35-65percent acetonitrile in H20 (add 0.5percent NH3 H20, v/v)] to give: (R)-N-(2,2 -dimethylquinuclidin-3 -yl) -2-methylbenzo [d] oxazole -5 -carboxamide (compound (i?)-32) (30 mg, 30percent yield) as a white solid: cSFC analytical (A) tR=2.44 min., purity: 96.08percent; LCMS (J): tR=0.995 min., 314.1 m/z (M+1); -NMR (CD3OD, 400 MHz): delta 8.10 (s, IH), 7.87-7.85 (m, IH), 7.67 (d, J=8.8 Hz, IH), 4.07 (s, IH), 3.33-3.33 (m, 2H), 2.85-2.85 (m, 2H), 2.69 (s, 3H), 2.09-2.09 (m, IH), 1.97-1.86 (m, 3H), 1.67-1.64 (m, IH), 1.51 (s, 3H), 1.32 (s, 3H).
90322-32-0 2-Methylbenzo[d]oxazole-5-carboxylic acid 23282284, abenzoxazole compound, is more and more widely used in various fields.
Reference£º
Patent; FORUM PHARMACEUTICALS, INC.; ACHARYA, Raksha; BURNETT, Duane, A.; BURSAVICH, Matthew, Gregory; COOK, Andrew, Simon; HARRISON, Bryce, Alden; KOENIG, Gerhard; MCRINER, Andrew, J.; (400 pag.)WO2016/100184; (2016); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem