Silica-sulfuric acid catalyzed microwave-assisted synthesis of substituted benzoxazoles and their antimicrobial activity was written by Anand, M.;Ranjitha, A.;Himaja, M.. And the article was included in International Research Journal of Pharmacy in 2011.COA of Formula: C9H9NO This article mentions the following:
Benzoxazole derivatives were designed for a study of their biol. activity, the synthesis of the target compounds was achieved by a microwave-mediated method using sulfated silica (solid acid) as catalyst and ortho esters and 2-aminophenol derivatives as starting materials and the products thus obtained were confirmed by 1H-NMR and MS. The title compounds were screened against Staphylococcus aureus, Escherichia coli, Candida albicans and Candida glabrata (yeast) and it was discovered that these compounds displayed antimicrobial activity in comparison with Trimethoprim and Miconazole. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4COA of Formula: C9H9NO).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.COA of Formula: C9H9NO
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem