A common heterocyclic compound, the benzoxazole compound, name is 5-Nitro-2,3-dihydro-1,3-benzoxazol-2-one,cas is 3889-13-2, mainly used in chemical industry, its synthesis route is as follows.,3889-13-2
Synthesis of 5-aminobenzo[d]oxazol-2(3H)-one (39-2) (0488) The mixture of 39-1 (5.1 g, 28.31 mmol), Pd/C (0.5 g) and HCO2NH4 (8.9 g, 141.57 mmol) in MeOH (200 mL) was stirred at room temperature overnight. Filtered with kiselguhr, concentrated in vacuo, the residue was added 5% NaHCO3 solution, collected the solid and washed with water (50 mL), dried in vacuo to get compound 39-2 as a brown solid (4 g, yield 94%).
As the rapid development of chemical substances, we look forward to future research findings about 3889-13-2
Reference£º
Patent; Nivalis Therapeutics, Inc.; Wasley, Jan; Rosenthal, Gary J.; Sun, Xicheng; Strong, Sarah; Qiu, Jian; US9138427; (2015); B2;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem