The benzoxazole compound, cas is 5676-60-8 name is 2-Methylbenzo[d]oxazol-6-amine, mainly used in chemical industry, its synthesis route is as follows.,5676-60-8
EXAMPLE 4 Compound No. 4 N-[6-(2,6-dichlorophenyl)-2-[(2-methyl-6-benzoxazolyl)amino]pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea 210 mg of the amine of preparation 20 in Table 2 and 562 mg of the urea of preparation 1 in Table 1 are heated for 8 hours at 45 C. in 20 ml of ethanol containing 0.02 ml of concentrated HCl. After concentration under reduced pressure, the residue is chromatographed on silica gel, the eluent being CHCl3/MeOH: 98/2 (v/v). 300 mg of product in the form of a yellow solid are isolated. MH+: 536.
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Reference£º
Patent; SANOFI-AVENTIS; US2008/176874; (2008); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem