In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Copper-catalyzed aminothiolation of terminal alkynes with tunable regioselectivity, published in 2019, which mentions a compound: 27231-36-3, mainly applied to thiazolobenzimidazole preparation regioselective; terminal alkyne regioselective cycloaddition mercaptobenzimidazole aminothiolation copper catalyst, Formula: C8H8N2S.
A simple, mild, and efficient copper(I)-catalyzed aminothiolation of terminal alkynes R1CCH (R1 = HOCH2CH2, Me3Si, cyclohexen-1-yl, Ph, pyridin-2-yl, etc.) with 5-R2-substituted 2-mercaptobenzimidazoles (R2 = H, Me, MeO, O2N) gave both 2- and 3-substituted thiazolo[3,2-a]benzimidazoles I, where complementary regioselectivities could be achieved by using sterically different phenanthroline-based ligands, such as 1,10-phenanthroline and 2,9-diisopropyl-1,10-phenanthroline.
《Copper-catalyzed aminothiolation of terminal alkynes with tunable regioselectivity》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(2-Mercapto-5-methylbenzimidazole)Formula: C8H8N2S.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem