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MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem