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Anilide compounds and drugs containing the same
The invention relates to a novel anilide compound and a pharmaceutical composition comprising the same. The invention relates to a compound represented by the following general formula: represents a divalent residue of benzene with a substituent(s), heterocycle-condensed benzene which may or may not have a substituent, pyridine which may or may not have a substituent, cyclohexane or naphthalene or Ar represents an aryl group which may or may not have a substituent;X represents ?NH?, oxygen atom or sulfur atom;Y represents ?NR4?, oxygen atom, sulfur atom, sulfoxide or sulfone;Z represents single bond or ?NR5?;R4 represents hydrogen atom, a lower alkyl group, an aryl group or a silylated lower alkyl group which may or may not have a substituent;R5 represents hydrogen atom, a lower alkyl group, an aryl group or a silylated lower alkyl group which may or may not have a substituent; andn represents an integer of 0 to 15.The inventive compounds are useful in the form of pharmaceutical composition, specifically as acyl coenzyme A cholesterol acyltransferase (ACAT) inhibitor.
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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem