One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: Methyl benzo[d]oxazole-5-carboxylate, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 924869-17-0, Name is Methyl benzo[d]oxazole-5-carboxylate, molecular formula is C9H7NO3
Synthesis, Structure Revision, and Cytotoxicity of Nocarbenzoxazole G
The total synthesis of nocarbenzoxazoles F (1) and G (2), originally obtained from the marine-derived halophilic bacterial strain Nocardiopsis lucentensis DSM 44048, was achieved via a simple and versatile route involving microwave-assisted construction of a benzoxazole skeleton, followed by carbon-carbon bond formation with the corresponding aryl bromides. Unfortunately, the 1H and 13C NMR spectra of natural nocarbenzoxazole G did not agree with those of the synthesized compound. In particular, the spectra of the isolated and synthesized compounds showed considerable differences in the signals from the protons and carbons in the aryl group. The revised structure was validated by the total synthesis of the actual nocarbenzoxazole G (8c) molecule, which is a regioisomer of the compound that was reported earlier as nocarbenzoxazole G. The synthesized derivatives showed specific cytotoxicity to the human cervical carcinoma cell line, HeLa, but did not have any remarkable effect on the other cell lines.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: Methyl benzo[d]oxazole-5-carboxylate, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 924869-17-0, in my other articles.
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem