With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2382-96-9,Benzo[d]oxazole-2-thiol,as a common compound, the synthetic route is as follows.
General procedure: A mixture of 2-mercaptobenzoxazole (2a, X = O), 2-mercaptobenzthiazole (2b,X = S) (10 mmol), 2-chloroacetic acid (10 mmol), K2CO3 (10 mmol), DMF (10 mL),and TBAB as a PTC was stirred for 1-2 h at r.t. After completion of reaction, the mixturewas cooled to r.t. and treated with acetic acid until neutralized. The separated solid wasfiltered, washed with water (2 ¡Á 40 mL), and dried to obtain crude 3a,b. The latter onrecrystallization from suitable solvent gave pure 3a,b., 2382-96-9
2382-96-9 Benzo[d]oxazole-2-thiol 712377, abenzoxazole compound, is more and more widely used in various fields.
Reference£º
Article; Rafeeq, Mohammad; Ramana Reddy, Chittireddy Venkata; Dubey, Pramod Kumar; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 190; 11; (2015); p. 1857 – 1864;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem